ReviewChildren (Basel, Switzerland)2018
Bilateral Wilms Tumor: A Surgical Perspective.
Review in Children (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Characteristics and outcome of synchronous bilateral Wilms tumour in the SIOP WT 2001 Study: Report from the SIOP Renal Tumour Study Group (SIOP-RTSG).British journal of cancer · 2024Trial
- Clinical and prognostic characteristics of bilateral Wilms tumor: a multi-center institutional retrospective cohort study experience from China.World journal of pediatrics : WJP · 2025Article
- A novel nephrometry scoring system outperforms RENAL score, PADUA score, and SPARE score for feasibility prediction of nephron-sparing surgery in children with bilateral Wilms tumor.Quantitative imaging in medicine and surgery · 2024Article
- Robot-assisted resection of renal tumor in children and comparison with laparoscopic surgery.BMC surgery · 2024Article
- Concomitant Wilms tumor and autosomal dominant polycystic kidney disease.Pediatric blood & cancer · 2024Article
- Preoperative three-dimensional modelling and virtual reality planning aids nephron sparing surgery in a child with bilateral Wilms tumour.BMJ case reports · 2024Article
- Single-cell transcriptomes of kidneys in a 6-month-old boy with Denys-Drash syndrome reveal stromal cell heterogeneity in the tumor microenvironment.Clinical kidney journal · 2024Article
- Surgery in Bilateral Wilms Tumor-A Single-Center Experience.Children (Basel, Switzerland) · 2023Article
- A Single Center Experience With Bilateral Wilms Tumor.The American surgeon · 2023Article
- Prechemotherapy Transperitoneal Robotic-Assisted Partial Nephrectomy (RAPN) for a Wilms Tumor: Surgical and Oncological Outcomes in a Four-Year-Old Patient.Pediatric reports · 2023Article
- Robotic approach with neoadjuvant chemotherapy in adult Wilms' tumor: A feasibility study report and a systematic review of the literature.Asian journal of urology · 2023Review
- Impact of Time to Surgery on Outcome in Wilms Tumor Treated with Preoperative Chemotherapy.Cancers · 2023Article
- Nephron-sparing surgery for Wilms tumor.Frontiers in pediatrics · 2023Review
- Advances in the treatment of pediatric solid tumors: A 50-year perspective.Journal of surgical oncology · 2022Article
- Article
- Multidisciplinary Treatment Strategies for Wilms Tumor: Recent Advances, Technical Innovations and Future Directions.Frontiers in pediatrics · 2022Review
- Many faces of Wilms Tumor: Recent advances and future directions.Annals of medicine and surgery (2012) · 2021Review
- [Clinical effect of multicenter multidisciplinary treatment in children with renal malignant tumors].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Bilateral Nephroblastoma with Dilated Cardiomyopathy as an Indication for Off-Protocol Treatment: A Case Report.International journal of environmental research and public health · 2020Article
- Nephron-Sparing Surgery in Nonsyndromic Unilateral Wilms' tumor: An Insight into the Ongoing Surgical Controversy.Journal of Indian Association of Pediatric SurgeonsReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Historically, the management of bilateral Wilms tumor (BWT) was non-standardized and suffered from instances of prolonged chemotherapy and inconsistent surgical management which resulted in suboptimal renal and oncologic outcomes. Because of the risk of end-stage renal disease associated with the management of BWT, neoadjuvant chemotherapy and nephron-sparing surgery have been adopted as the guiding management principles. This management strategy balances acceptable oncologic outcomes against the risk of end-stage renal disease. A recent multi-institutional Children's Oncology Group study (AREN0534) has confirmed the benefits of standardized 3-drug neoadjuvant chemotherapy and the utilization of nephron-sparing surgery in BWT patients; however, less than 50% of patients underwent bilateral nephron-sparing surgery. The coordination of neoadjuvant chemotherapy and the timing and implementation of bilateral nephron-sparing surgery are features of BWT management that require collaboration between oncologists and surgeons. This review discusses the surgical management strategy in the context of BWT disease biology, with an emphasis on timepoints during therapy at which surgical decision making can greatly impact this disease and minimize long-term toxicities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.