Evidence map›Paper›PMID 30249984›Full record

ArticleMolecules (Basel, Switzerland)2018

Inferring microRNA-Environmental Factor Interactions Based on Multiple Biological Information Fusion.

Haiqiong Luo, Wei Lan, Qingfeng Chen, Zhiqiang Wang, Zhixian Liu, Xiaofeng Yue, Lingzhi Zhu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Molecular Computing and Bioinformatics.Molecules (Basel, Switzerland) · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haiqiong LuoSchool of information and management, Guangxi Medical University, Nanning 530021, China. hqluo@163.com.
Wei LanSchool of Computer, Electronic and Information, Guangxi University, Nanning 530004, China. lanwei@gxu.edu.cn.
Qingfeng ChenSchool of Computer, Electronic and Information, Guangxi University, Nanning 530004, China. qingfeng@gxu.edu.cn.
Zhiqiang WangState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi University, Nanning 530004, China. zhqwang@gxu.edu.cn.
Zhixian LiuSchool of electronic and information engineering, Qinzhou University, Qingzhou 535011, China. qzxylzx@163.com.
Xiaofeng YueSchool of Automation, Huazhong University of Science and Technology, Wuhan 430074, China. xfyue@hust.edu.cn.
Lingzhi ZhuDepartment of Computer and Information Science, Hunan Institute of Technology, Hengyang 421008, China. lz_zhu@csu.edu.cn.

Funding

National Natural Science Foundation of China 61702122 and 61751314Natural Science Foundation of Guangxi Province 2017GXNSFDA198033
6 · The paper itself

Abstract

Accumulated studies have shown that environmental factors (EFs) can regulate the expression of microRNA (miRNA) which is closely associated with several diseases. Therefore, identifying miRNA-EF associations can facilitate the study of diseases. Recently, several computational methods have been proposed to explore miRNA-EF interactions. In this paper, a novel computational method, MEI-BRWMLL, is proposed to uncover the relationship between miRNA and EF. The similarities of miRNA-miRNA are calculated by using miRNA sequence, miRNA-EF interaction, and the similarities of EF-EF are calculated based on the anatomical therapeutic chemical information, chemical structure and miRNA-EF interaction. The similarity network fusion is used to fuse the similarity between miRNA and the similarity between EF, respectively. Further, the multiple-label learning and bi-random walk are employed to identify the association between miRNA and EF. The experimental results show that our method outperforms the state-of-the-art algorithms.

Indexed as

AlgorithmsBiological ProductsComputational BiologyGene Expression RegulationHumansMicroRNAsBiological ProductsMicroRNAsenvironmental factormicroRNAsimilarity networkstructure information

Identifiers

PMID30249984
PMCPMC6222788

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.