ArticleJournal of epidemiology2019
Prevalence of Congenital Anomalies in the Japan Environment and Children's Study.
Article in Journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- Breastfeeding and children's sleep duration at 1 year of age: A nationwide birth cohort - The Japan Environment and Children's Study.European journal of clinical nutrition · 2026Article
- Caesarean section may be associated with suspected motor developmental delay at 3 years of age in the Japan Environment and Children's Study.Scientific reports · 2026Article
- Article
- Maternal Psychological Distress Before and After Childbirth and Neurodevelopmental Delay in Toddlers.JAMA network open · 2025Article
- The impact of the number of non-opioid psychotropic medications and their co-exposures during pregnancy on short-term outcomes in full-term neonates.Scientific reports · 2025Article
- Low glucose challenge test result as a potential risk factor for delays in early child development: the Japan environment and children's study.Journal of diabetes and metabolic disorders · 2025Article
- Association between the duration of mothers' digital media use while with their children and two-year-old children's development from the Japan Environment and Children's Study.Scientific reports · 2025Article
- Prospective association of daily toothbrushing frequency and the prevalence of childhood functional constipation: the Japan Environment and Children's Study.Scientific reports · 2025Article
- Final Report of Trends in Pregnancy and Birth Survey after the Great East Japan Earthquake and Fukushima Daiichi Nuclear Power Plant Accident: The Fukushima Health Management Survey.Fukushima journal of medical science · 2025Article
- Association between maternal distress during pregnancy and lower 5-min-Apgar score of the offspring: the Japan Environment and Children's Study.Environmental health and preventive medicine · 2025Article
- Impact of maternal body mass index and gestational comorbidities on the birth prevalence of orofacial clefts in the Japan Environment and Children's Study.Environmental health and preventive medicine · 2025Article
- Prevalence and trends of major congenital anomalies in Brazil: A study from 2011 to 2020.PloS one · 2025Article
- Pharmacovigilance Pregnancy Data in a Population of Japanese Patients With Chronic Inflammatory Disease Exposed to Certolizumab Pegol.International journal of rheumatic diseases · 2025Article
- Association of air purifier usage during pregnancy with adverse birth outcomes: the Japan Environment and Children's Study.BMC public health · 2024Article
- Breastfeeding and Children's Cognitive Development up to the Age of 4 Years: The Japan Environment and Children's Study.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2024Article
- Nationwide Birth Prevalence of Crucial Congenital Heart Defects From 2014 to 2018 in Korea.Korean circulation journal · 2024Article
- Effectiveness of Watching a Kumagai Method Video for Long-Nipple Bottle-Feeding for Children with Cleft Lip and Palate: A Pilot Experimental Before-After Trial Study.Children (Basel, Switzerland) · 2024Article
- Maternal exposure to smoking and wheezing phenotypes in children: a cohort study of the Japan Environment and Children's Study.BMC pediatrics · 2024Article
- Prevalence and death rate of birth defects from population-based surveillance in Hunan Province, China, 2010-2020.Scientific reports · 2024Article
- Impact of Habitual Yogurt Intake in Mother-Child Dyads on Incidence of Childhood Otitis Media: The Japan Environment and Children's Study (JECS).Probiotics and antimicrobial proteins · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aims of the present report were to estimate the prevalence of congenital anomalies (CAs) among infants in Japan using data from the Japan Environment and Children's Study (JECS) and to evaluate the validity of CA classification within JECS.
methodsData on CAs were collected at delivery and at age 1 month from the medical records of 101,825 infants at 15 regional centers. The analyses focused on 61 CAs, selected on the basis of reported associations with environmental exposure. Prevalence per 10,000 pregnancies (including miscarriages, stillbirths, and live births) was stratified according to four reporting patterns (at delivery, at age 1 month, at either, and at both). To evaluate the accuracy of observed CA prevalence, the medical records of 179 cases from a single JECS regional center underwent independent, retrospective re-evaluation.
resultsThe prevalence of major CAs in four reporting patterns (at delivery, at age 1 month, at either, and at both) was 2.4, 2.6, 3.5, and 1.4 for myelomeningocele/spina bifida; 4.3, 4.2, 5.3, and 3.2 for cleft palate; 18.1, 17.4, 19.5, and 15.1 for cleft lip with or without cleft palate; 73.4, 100.3, 120.8, and 52.8 for congenital heart disease; and 10.5, 14.1, 15.0, and 9.6 for Down's syndrome, respectively. In the subsample re-evaluation, CA diagnoses were confirmed for 92.7%, 93.3%, 90.5%, and 97.8% of cases in the four reporting patterns (at delivery, at age 1 month, at either, and at both), respectively.
conclusionsThe present report generated reliable data concerning the prevalence of major CAs in JECS.
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