ArticleIndian journal of ophthalmology2018
Allergic reactions to atropine eye drops for retardation of progressive myopia in children.
Article in Indian journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of the efficacy and safety of different doses of atropine for myopic control in children: a meta-analysis.Frontiers in pharmacology · 2023Pooled it
- Assessing the reliability of non-cycloplegic refraction in children: a machine learning approach based on non-cycloplegic parameters.Frontiers in public health · 2026Article
- A systemic pharmacovigilance assessment of ophthalmic atropine: signal detection and clinical prioritization from the FAERS database.Frontiers in medicine · 2026Article
- Exploration of correlated factors of axial length changes after repeated low-level red-light irradiation in the real world.BMC ophthalmology · 2025Article
- Short-term effects of ophthalmic topical 0.01% atropine on the ocular surface, pupil size, and subsequent subjective quality of vision in young myopic Chinese adults.Frontiers in medicine · 2024Article
- Parents Know Best: Uncovering a Rare Allergy During Anesthesia Consultation.Case reports in pediatrics · 2024Article
- Pupillary Dilation in Research: More than Meets the Eye.Current eye research · 2022Article
- Myopia in India.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- Effect of Atropine Eye Drops Combined with VR-Based Binocular Visual Function Balance Training for Prevention and Control of Juvenile Myopia.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Corneal Penetration of Low-Dose Atropine Eye Drops.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report clinical manifestations of ocular allergy to atropine eye drops used for retardation of progressive myopia in children.
methodsMyopic children, who developed bothersome itching that subsided promptly after cessation of atropine eye drops, were included. History of systemic or ocular allergy, preexisting ocular conditions, and clinical features of allergy were noted.
resultsSix children, age 5-15 years, were included. Four developed allergy to 1% atropine sulfate eye drops and two to 0.01% concentration of atropine sulfate. The onset of allergy was within a month to as late as 4 years after using atropine eye drops. The severity of allergy was higher with 1% concentration. The most common symptoms of atropine allergy were itching and burning. The most common signs were lid swelling and hyperemia. The allergic manifestations promptly reversed with the stoppage of eye drops. Reintroduction was possible in three patients, either by reducing the concentration of atropine or using benzalkonium free formulation.
conclusionAllergy to atropine eye drops in children may develop within a few weeks or after many years of usage. Prompt cessation followed by a reintroduction and continuation of therapy may be possible in few patients.
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