Evidence map›Paper›PMID 30249781›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2018

The mechanical impact of

Elizabeth A Lawrence, Erika Kague, Jessye A Aggleton, Robert L Harniman, Karen A Roddy, Chrissy L Hammond

Open access · hybridAbstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. A Systematic Review on the Role of the Stria Vascularis in Menière's Disease Pathogenesis.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. A Zebrafish Mutant in the Extracellular Matrix Protein GeneAnimals : an open access journal from MDPI · 2023
    Article
  12. Article
  13. Why Animal Experiments Are Still Indispensable in Bone Research: A Statement by the European Calcified Tissue Society.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Review
  14. Zebrafish crocc2 mutants exhibit divergent craniofacial shape, misregulated variability, and aberrant cartilage morphogenesis.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  15. Review
  16. Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway.Frontiers in cell and developmental biology · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elizabeth A LawrenceSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, UK.
Erika KagueSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, UK.ORCID 0000-0002-0266-9424
Jessye A AggletonSchool of Anthropology and Archaeology, University of Bristol, Bristol BS8 1UU, UK.ORCID 0000-0002-9765-3758
Robert L HarnimanSchool of Chemistry, University of Bristol, Bristol BS8 1TS, UK.
Karen A RoddySchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, UK.
Chrissy L HammondSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, UK chrissy.hammond@bristol.ac.uk.ORCID 0000-0002-4935-6724
University of Bristol · GB

Funding

Arthritis Research UK 19947Arthritis Research UK 21211Medical Research Council MR/L002566/1Versus Arthritis 19476Versus Arthritis 21937Wellcome Trust
6 · The paper itself

Abstract

Collagen is the major structural component of cartilage, and mutations in the genes encoding type XI collagen are associated with severe skeletal dysplasias (fibrochondrogenesis and Stickler syndrome) and early-onset osteoarthritis (OA). The impact of the lack of type XI collagen on cell behaviour and mechanical performance during skeleton development is unknown. We studied a zebrafish mutant for

Indexed as

ZebrafishAnimalsArthritisBiomechanical PhenomenaCollagen Type XIDisease Models, AnimalJointsOsteoporosisZebrafish Proteinscol11a2 protein, zebrafishCollagen Type XIZebrafish ProteinsbiomechanicscartilagecollagendevelopmentStickler syndromezebrafish

Identifiers

PMID30249781
PMCPMC6158203
OpenAlexW2949273764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.