ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2018
New functions for the proprioceptive system in skeletal biology.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed.
- The efficacy of combined physiotherapeutic scoliosis-specific exercises and manual therapy in adolescent idiopathic scoliosis.BMC musculoskeletal disorders · 2024Trial
- Cellular and molecular mechanisms of muscle spindle development and function.Physiology (Bethesda, Md.) · 2026Review
- Low physical activity and risk of falls among older adults in a high-altitude district of Peru: a secondary analysis of the Aunqui-Andes study.BMC geriatrics · 2026Article
- The role of proprioception in the management and rehabilitation of adolescent idiopathic scoliosis.Frontiers in rehabilitation sciences · 2026Article
- Deletion of a conserved genomic region associated with adolescent idiopathic scoliosis leads to vertebral rotation in mice.Human molecular genetics · 2024Article
- Research progress in female pelvic floor rehabilitation aids.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Review
- Effect of Whole-Body Vibration Exercise on Pain, Disability, Balance, Proprioception, Functional Performance and Quality of Life in People with Non-Specific Chronic Low Back Pain: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Biophysical model of muscle spindle encoding.Experimental physiology · 2024Review
- Mechanosensory encoding in ex vivo muscle-nerve preparations.Experimental physiology · 2024Review
- Experimental Physiology special issue: 'Mechanotransduction, muscle spindles and proprioception'.Experimental physiology · 2024Article
- SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation.Fluids and barriers of the CNS · 2023Article
- The making of a proprioceptor: a tale of two identities.Trends in neurosciences · 2023Review
- Article
- Assessment of Balance Parameters in Children with Weakened Axial Muscle Tone Undergoing Sensory Integration Therapy.Children (Basel, Switzerland) · 2023Article
- Muscle spindles and their role in maintaining robust locomotion.The Journal of physiology · 2023Review
- Osteoporosis in Light of a New Mechanism Theory of Delayed Onset Muscle Soreness and Non-Contact Anterior Cruciate Ligament Injury.International journal of molecular sciences · 2022Article
- Sensory innervation of the human palmar aponeurosis in healthy individuals and patients with palmar fibromatosis.Journal of anatomy · 2022Article
- Mechanogenetics: harnessing mechanobiology for cellular engineering.Current opinion in biotechnology · 2022Review
- Paraspinal muscle morphology and composition in adolescent idiopathic scoliosis: A histological analysis.JOR spine · 2021Article
- Does Compression Sensory Axonopathy in the Proximal Tibia Contribute to Noncontact Anterior Cruciate Ligament Injury in a Causative Way?-A New Theory for the Injury Mechanism.Life (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Muscle spindles and Golgi tendon organs (GTOs) are two types of sensory receptors that respond to changes in length or tension of skeletal muscles. These mechanosensors have long been known to participate in both proprioception and stretch reflex. Here, we present recent findings implicating these organs in maintenance of spine alignment as well as in realignment of fractured bones. These discoveries have been made in several mouse lines lacking functional mechanosensors in part or completely. In both studies, the absence of functional spindles and GTOs produced a more severe phenotype than that of spindles alone. Interestingly, the spinal curve phenotype, which appeared during peripubertal development, bears resemblance to the human condition adolescent idiopathic scoliosis. This similarity may contribute to the study of the disease by offering both an animal model and a clue as to its aetiology. Moreover, it raises the possibility that impaired proprioceptive signalling may be involved in the aetiology of other conditions. Overall, these new findings expand considerably the scope of involvement of proprioception in musculoskeletal development and function.This article is part of the Theo Murphy meeting issue 'Mechanics of development'.
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