Evidence map›Paper›PMID 30249755›Full record

ArticleBioscience reports2018

FOXF2 inhibits proliferation, migration, and invasion of Hela cells by regulating Wnt signaling pathway.

Jun Zhang, Chunxia Zhang, Lin Sang, Ling Huang, Juan Du, Xingbo Zhao

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jun ZhangDepartment of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, No. 324, Jing wu wei qi Road, Ji'nan City 250021, Shandong Province, China.
Chunxia ZhangDepartment VI of Obstetrics, Tai'an City Central Hospital, No. 29, Long tan Road, Tai'an City 271000, Shandong Province, China.
Lin SangDepartment of Obstetrics and Gynecology, The Second People's Hospital of Hefei City Affiliated to Anhui Medical University, Guang de Road, Yao hai District, Hefei City 230000, Anhui Province, China.
Ling HuangDepartment VI of Obstetrics, Tai'an City Central Hospital, No. 29, Long tan Road, Tai'an City 271000, Shandong Province, China.
Juan DuDepartment VI of Obstetrics, Tai'an City Central Hospital, No. 29, Long tan Road, Tai'an City 271000, Shandong Province, China.
Xingbo ZhaoDepartment of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, No. 324, Jing wu wei qi Road, Ji'nan City 250021, Shandong Province, China zhaoxingboa123@163.com.ORCID 0000-0001-7321-5860
Taian City Central Hospital · CNShandong University · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article was aimed to study the FOXF2 effects on cervical cancer. Tumor tissues and adjacent tissues of 41 cervical cancer patients were collected. Human endometrial epithelial cells (hEEC) and Hela cells were cultured. FOXF2 expression vector and its empty vector were transfected into Hela cells, and named as pcDNA 3.1-FOXF2 group and Vector group, respectively. Hela cells without any treatment were set as Blank group. qRT-PCR was used to detect mRNA expression. Nude mouse xenograft assay was performed to test Hela cells proliferation ability

Indexed as

AgedAnimalsApoptosisbeta CateninCell MovementCell ProliferationFemaleForkhead Transcription FactorsGene Expression Regulation, NeoplasticHeLa CellsHumansMiceMicroRNAsMiddle AgedNeoplasm InvasivenessUterine Cervical Neoplasmsbeta CateninCTNNB1 protein, humanForkhead Transcription FactorsFOXF2 protein, humanMicroRNAsCervical cancerFOXF2InvasionProliferationWnt signaling pathway

Identifiers

PMID30249755
PMCPMC6200704
OpenAlexW2892407361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.