Evidence map›Paper›PMID 30249749›Full record

ArticleInfection and immunity2018

Autoinducer 2 (AI-2) Production by Nontypeable Haemophilus influenzae 86-028NP Promotes Expression of a Predicted Glycosyltransferase That Is a Determinant of Biofilm Maturation, Prevention of Dispersal, and Persistence

Bing Pang, Chelsie E Armbruster, Gayle Foster, Brian S Learman, Uma Gandhi, W Edward Swords

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. The Role of Non-TypeableFrontiers in cellular and infection microbiology · 2021
    Review
  6. NontypeableBiofilm · 2020
    Article
  7. Panel 7 - Pathogenesis of otitis media - a review of the literature between 2015 and 2019.International journal of pediatric otorhinolaryngology · 2020
    Review
  8. Panel 8: Vaccines and immunology.International journal of pediatric otorhinolaryngology · 2020
    Review
  9. Quorum Sensing as Antivirulence Target in Cystic Fibrosis Pathogens.International journal of molecular sciences · 2019
    Review
  10. Article
  11. The AI-2/Frontiers in cellular and infection microbiology · 2019
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bing Pang *Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Chelsie E Armbruster *Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0002-2165-2759
Gayle FosterDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Brian S LearmanDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Uma GandhiDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
W Edward SwordsDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA swords@uab.edu.
Wake Forest University · USUniversity of Alabama at Birmingham · US

Funding

Microbial interactions in otitis mediaR01DC010051 · NIDCD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ORNELLES, DAVID ARNOLD, SWORDS, WILLIAM E · 2009 to 2018
$3.3M
Bacterial biofilms in otitis mediaR01DC007444 · NIDCD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SWORDS, WILLIAM E · 2005 to 2014
$2.9M
NIDCD NIH HHS R01 DC007444NIDCD NIH HHS R01 DC010051
6 · The paper itself

Abstract

Nontypeable

Indexed as

AnimalsBacterial ProteinsBiofilmsCarbon-Sulfur LyasesCarrier ProteinsChinchillaGene Expression ProfilingGlycosyltransferasesHaemophilus InfectionsHaemophilus influenzaeHomoserineIntracellular Signaling Peptides and ProteinsLactonesMutationOtitis MediaReal-Time Polymerase Chain ReactionBacterial ProteinsCarbon-Sulfur LyasesCarrier ProteinsGlycosyltransferasesGstA protein, bacteriaHomoserineIntracellular Signaling Peptides and ProteinsLactonesLuxS protein, BacteriaN-octanoylhomoserine lactoneXylosebiofilmHaemophilus influenzaeotitis mediaquorum signal

Identifiers

PMID30249749
PMCPMC6246909
OpenAlexW2894466260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.