Evidence map›Paper›PMID 30249702›Full record

ArticleJournal of bacteriology2018

Getting Our Fingers on the Pulse of Slow-Growing Bacteria in Hard-To-Reach Places.

Tara Gallagher, Joann Phan, Katrine Whiteson

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Microbiology spectrum · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tara GallagherDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.
Joann PhanDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.
Katrine WhitesonDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA katrine@uci.edu.ORCID 0000-0002-5423-6014
University of California, Irvine · US

Funding

Dynamics of airway microbiota at pulmonary exacerbation in cystic fibrosisR01HL136647 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIPUMA, JOHN J · 2017 to 2020
$1.3M
Omics of pulmonary exacerbations in cystic fibrosisR56HL126754 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIPUMA, JOHN J · 2016 to 2016
$388k
NHLBI NIH HHS R01 HL136647NHLBI NIH HHS R56 HL126754
6 · The paper itself

Abstract

Chronic infections with slow-growing pathogens have plagued humans throughout history. However, assessing the identities and growth rates of bacteria in an infection has remained an elusive goal. Neubauer et al. (J. Bacteriol. 200:e00365-18, 2018, https://doi.org/10.1128/JB.00365-18) combine two cutting-edge approaches to make progress on both fronts: probing specific RNA molecules to assess the identity of actively transcribing microbes and measuring growth rates through incorporation of stable isotope labels. They found that growth rates of pathogens were relatively stable during antibacterial therapy. The article delves into a basic and unanswered question that gets to the heart of understanding infection: what are the microbial growth rates?

Indexed as

Cystic FibrosisStaphylococcal InfectionsHumansLipidsSputumStaphylococcus aureusLipidscystic fibrosisfatty acidsgrowth modelingstable isotopeStaphylococcus aureus

Identifiers

PMID30249702
PMCPMC6256019
OpenAlexW2892836507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.