Evidence map›Paper›PMID 30249693›Full record

ArticleAntimicrobial agents and chemotherapy2018

Activity of Moxifloxacin against

Arnold Louie, Brandon Duncanson, Jenny Myrick, Michael Maynard, Jocelyn Nole, David Brown, Stephan Schmidt, Michael Neely, C A Scanga, Charles Peloquin and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. DynamicAntibiotics (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Generating Robust and Informative NonclinicalAntimicrobial agents and chemotherapy · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Arnold LouieInstitute for Therapeutic Innovation, College of Medicine, University of Florida, Lake Nona, Florida, USA.
Brandon DuncansonInstitute for Therapeutic Innovation, College of Medicine, University of Florida, Lake Nona, Florida, USA.
Jenny MyrickInstitute for Therapeutic Innovation, College of Medicine, University of Florida, Lake Nona, Florida, USA.
Michael MaynardInstitute for Therapeutic Innovation, College of Medicine, University of Florida, Lake Nona, Florida, USA.
Jocelyn NoleInstitute for Therapeutic Innovation, College of Medicine, University of Florida, Lake Nona, Florida, USA.
David BrownInstitute for Therapeutic Innovation, College of Medicine, University of Florida, Lake Nona, Florida, USA.
Stephan SchmidtInfectious Disease Pharmacokinetics Laboratory, University of Florida College of Pharmacy, Gainesville, Florida, USA.
Michael NeelyDivision of Pediatric Infectious Diseases, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, California, USA.
C A ScangaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Charles PeloquinInfectious Disease Pharmacokinetics Laboratory, University of Florida College of Pharmacy, Gainesville, Florida, USA.ORCID 0000-0001-9002-7052
G L DrusanoInstitute for Therapeutic Innovation, College of Medicine, University of Florida, Lake Nona, Florida, USA gdrusano@ufl.edu.
University of Florida · USUniversity of Pittsburgh · USUniversity of Southern California · US

Funding

Optimizing Combination Therapy to Accelerate Clinical Cure of TuberculosisP01AI123036 · NIAID · UNIVERSITY OF FLORIDA · PI FLYNN, JOANNE L. · 2016 to 2020
$12.0M
NIAID NIH HHS P01 AI123036
6 · The paper itself

Abstract

A major goal for improving tuberculosis therapy is to identify drug regimens with improved efficacy and shorter treatment durations. Shorter therapies improve patient adherence to the antibiotic regimens, which, in turn, decreases resistance emergence.

Indexed as

Models, BiologicalModels, StatisticalAntitubercular AgentsColony Count, MicrobialCulture MediaDiffusion Chambers, CultureDose-Response Relationship, DrugDrug Dosage CalculationsDrug Resistance, BacterialHumansMetabolic Networks and PathwaysMicrobial Sensitivity TestsMoxifloxacinMycobacterium tuberculosisPhenotypeStreptomycinAntitubercular AgentsCulture MediaMoxifloxacinStreptomycinmoxifloxacinMycobacterium tuberculosispharmacodynamics

Identifiers

PMID30249693
PMCPMC6256764
OpenAlexW2889641677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.