Evidence map›Paper›PMID 30249689›Full record

ArticleAntimicrobial agents and chemotherapy2018

Rifampin Resistance in Staphylococci after Rifaximin Intake for Surgical Prophylaxis in Elective Colorectal Surgery.

Emma Padilla, Lluis Oms, Elena Espejo, Laura Gómez, Lurdes Pagespetit, Núria Boada, Feliu Bella, Josefa Pérez

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emma PadillaMicrobiology Laboratory, CATLAB, Viladecavalls, Spain epadilla@catlab.cat.ORCID 0000-0003-0521-1897
Lluis OmsSurgery Service, Hospital de Terrassa (Consorci Sanitari de Terrassa), Terrassa, Spain.
Elena EspejoInfectious Diseases Unit, Hospital de Terrassa (Consorci Sanitari de Terrassa), Terrassa, Spain.ORCID 0000-0001-9018-7515
Laura GómezSurgery Service, Hospital de Terrassa (Consorci Sanitari de Terrassa), Terrassa, Spain.
Lurdes PagespetitInfection Control Team, Infectious Diseases Unit, Hospital de Terrassa (Consorci Sanitari de Terrassa), Terrassa, Spain.
Núria BoadaInfection Control Team, Infectious Diseases Unit, Hospital de Terrassa (Consorci Sanitari de Terrassa), Terrassa, Spain.
Feliu BellaInfectious Diseases Unit, Hospital de Terrassa (Consorci Sanitari de Terrassa), Terrassa, Spain.
Josefa PérezMicrobiology Laboratory, CATLAB, Viladecavalls, Spain.
Consorci Sanitari de Terrassa · ESHospital de Viladecans · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of our study was to determine whether rifampin resistance emerges in human skin staphylococci after oral intake of rifaximin for surgical prophylaxis. Rifampin-resistant staphylococci appeared on the skin of 32 out of 74 patients (43.2%) two weeks after prophylactic treatment with rifaximin. In all cases, the resistant strains were coagulase-negative staphylococci. The resistance completely reverted after three months. This study shows the emergence of transient resistance to rifampin after rifaximin intake.

Indexed as

Administration, OralAdultAgedAged, 80 and overAnti-Bacterial AgentsAntibiotic ProphylaxisColorectal SurgeryDrug Resistance, Multiple, BacterialElective Surgical ProceduresFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedRifampinRifaximinAnti-Bacterial AgentsRifampinRifaximinantibiotic resistancerifampinrifaximinStaphylococcussurgical prophylaxis

Identifiers

PMID30249689
PMCPMC6256800
OpenAlexW2890456366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.