ArticleAntimicrobial agents and chemotherapy2018
A Large, Refractory Nosocomial Outbreak of Klebsiella pneumoniae Carbapenemase-Producing Escherichia coli Demonstrates Carbapenemase Gene Outbreaks Involving Sink Sites Require Novel Approaches to Infection Control.
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In one paragraph
Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it, 142 citations in OpenAlex.
- A systematic review of the effectiveness of cohorting to reduce transmission of healthcare-associatedInfection control and hospital epidemiology · 2020Pooled it
- Trial
- Impact of restricted antibiotic use, hand hygiene, and sink trap replacement on carbapenemase-producing Enterobacterales acquisition in parturients and newborns, Southeast Gabon (2022-2023).Antimicrobial resistance and infection control · 2026Article
- Prediction of genetic relatedness ofAntimicrobial agents and chemotherapy · 2026Article
- Biofilm removal in hospital sink drains drives unintended surges in antibiotic resistance.npj antimicrobials and resistance · 2026Article
- Leveraging real-time genomic surveillance to combat infectious diseases and antimicrobial resistance in cancer patients.Frontiers in public health · 2026Article
- Paradoxical carbapenemase activity detected by modified carbapenemase inactivation (mCIM) method inJournal of clinical microbiology · 2025Article
- A network analysis of carbapenem-resistant Klebsiella pneumoniae among healthcare facilities.Scientific reports · 2025Observational
- The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens.npj antimicrobials and resistance · 2025Review
- Genomics for antimicrobial resistance-progress and future directions.Antimicrobial agents and chemotherapy · 2025Review
- The Antimicrobial Resistance-Water-Corporate Interface: Exploring the Connections Between Antimicrobials, Water, and Pollution.Tropical medicine and infectious disease · 2025Review
- A persistent sink reservoir as a potential source ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Impact of high-speed nanodroplets on various pathogenic bacterial cell walls.Journal of bacteriology · 2024Article
- The drainome: longitudinal metagenomic characterization of wastewater from hospital ward sinks to characterize the microbiome and resistome and to assess the effects of decontamination interventions.The Journal of hospital infection · 2024Article
- Successful control of an environmental reservoir of NDM-producing Klebsiella pneumoniae associated with nosocomial transmissions in a low-incidence setting.Antimicrobial resistance and infection control · 2024Article
- An outbreak of blaAntimicrobial resistance and infection control · 2024Article
- Is routine screening forIranian journal of microbiology · 2024Article
- Genomic epidemiology and longitudinal sampling of ward wastewater environments and patients reveals complexity of the transmission dynamics ofJAC-antimicrobial resistance · 2024Article
- Carbapenemase producingInfection prevention in practice · 2024Article
- Infection prevention and control and related practices in African neonatal units: The Pan-African neonatal care assessment study (PANCAS).International journal of hygiene and environmental health · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 7 institutions in 2 countries.
V Decraene *Field Service North West, Public Health England, Liverpool, United Kingdom.
H T T Phan *Nuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.
R George *Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
D H Wyllie *Nuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0002-9155-6228
O AkinremiNational Institute for Health Research, Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.
Z AikenManchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
P ClearyField Service North West, Public Health England, Liverpool, United Kingdom.
A DodgsonNuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.
L PankhurstNuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.ORCID 0000-0001-5898-2535
D W CrookNuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.
C LenneyManchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
A S WalkerNuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.
N WoodfordNational Institute for Health Research, Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom.
R SebraIcahn Institute, Department of Genetics and Genomic Sciences, Icahn School of Medicine Mount Sinai, New York, New York, USA.
F Fath-OrdoubadiManchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
A J MathersDivision of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
A C SealeLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
M GuiverPublic Health Laboratory Manchester, Public Health England, Manchester Royal Infirmary, Manchester, United Kingdom.
A McEwanManchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
V WattsField Service North West, Public Health England, Liverpool, United Kingdom.
W WelfarePublic Health England North West, Manchester, United Kingdom.
N Stoesser *Nuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom nicole.stoesser@ndm.ox.ac.uk.ORCID 0000-0002-4508-7969
J Cawthorne *Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
TRACE Investigators’ Group
John Radcliffe Hospital · GBManchester University NHS Foundation Trust · GBPublic Health England · GBManchester Royal Infirmary · GBIcahn School of Medicine at Mount Sinai · USManchester Academic Health Science Centre · GBUniversity of Virginia Health System · US
Funding
Department of Health HPRU-2012-10041
Abstract
Carbapenem-resistant
Indexed as
Disease Outbreaksbeta-LactamasesCross InfectionDisease ReservoirsDNA, BacterialEscherichia coliEscherichia coli InfectionsGene ExpressionGene Transfer, HorizontalGenotypeHospitals, UniversityHumansInfection ControlKlebsiella pneumoniaeMedical WastePhylogenybeta-lactamase KPC-2, Klebsiella pneumoniaebeta-LactamasesDNA, BacterialMedical WasteWastewaterantimicrobial resistancecarbapenemase-producing Enterobacteriaceaegenome sequencinginfection controlmolecular epidemiology
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.