ArticleProceedings of the National Academy of Sciences of the United States of America2018
MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Interferons in health and disease.Cell · 2025Review
- Exploring the prevalence of atopic disease among adult cancer survivors: insights from the 2021 NHIS.PloS one · 2025Article
- Fecal microbiota transplantation ameliorates type 2 diabetes via metabolic remodeling of the gut microbiota in db/db mice.BMJ open diabetes research & care · 2023Article
- The gut-lung axis in influenza A: the role of gut microbiota in immune balance.Frontiers in immunology · 2023Review
- How Gut Microbiota Are Shaped by Pattern Recognition Receptors in Colitis and Colorectal Cancer.Cancers · 2022Review
- Of Mice and MAVS-Diabetic Kidney Disease and the Leaky Gut.Journal of the American Society of Nephrology : JASN · 2022Article
- The MAVS Immune Recognition Pathway in Viral Infection and Sepsis.Antioxidants & redox signaling · 2021Review
- Implications of Gut Microbiota in Complex Human Diseases.International journal of molecular sciences · 2021Review
- Calcipotriol and iBRD9 reduce obesity in Nur77 knockout mice by regulating the gut microbiota, improving intestinal mucosal barrier function.International journal of obesity (2005) · 2020Article
- Impact of the microbiome on cancer progression and response to anti-cancer therapies.Advances in cancer research · 2019Review
- ZFP90 drives the initiation of colitis-associated colorectal cancer via a microbiota-dependent strategy.Gut microbesArticle
Corrections and comments
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Authors and funding
25 authors at 7 institutions in 4 countries.
Funding
Abstract
Prominent changes in the gut microbiota (referred to as "dysbiosis") play a key role in the development of allergic disorders, but the underlying mechanisms remain unknown. Study of the delayed-type hypersensitivity (DTH) response in mice contributed to our knowledge of the pathophysiology of human allergic contact dermatitis. Here we report a negative regulatory role of the RIG-I-like receptor adaptor mitochondrial antiviral signaling (MAVS) on DTH by modulating gut bacterial ecology. Cohousing and fecal transplantation experiments revealed that the dysbiotic microbiota of
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Registered trials
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