ArticleProceedings of the National Academy of Sciences of the United States of America2018
Neural basis of location-specific pupil luminance modulation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- Brain-wide arousal signals are segregated from movement planning in the superior colliculus of the macaque.eLife · 2026Article
- Imaging the spatiotemporal dynamics of covert attention with a pupillometric probing paradigm.iScience · 2026Article
- Presaccadic Attention Shifts Up- and Downwards: Evidence From the Pupil Light Response.Psychophysiology · 2025Article
- Challenges in using pupil dilation responses to sounds as a reliable alternative to standard audiometric tests.Heliyon · 2025Article
- Effects of chewing on postural learning: An experimental pre-post intervention study.PloS one · 2025Article
- Age-related changes in pupil dynamics and task modulation across the healthy lifespan.Frontiers in neuroscience · 2024Article
- Time-on-task effects on human pupillary and saccadic metrics after theta burst transcranial magnetic stimulation over the frontal eye field.IBRO neuroscience reports · 2023Article
- Fatigue and Arousal Modulations Revealed by Saccade and Pupil Dynamics.International journal of environmental research and public health · 2022Article
- The eyes reflect an internal cognitive state hidden in the population activity of cortical neurons.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- The relationship between pupillary baseline manipulated by mental effort or luminance and subsequent pupillary responses.Journal of vision · 2022Article
- Article
- Investigating the role of human frontal eye field in the pupil light reflex modulation by saccade planning and working memory.Frontiers in human neuroscience · 2022Article
- Superior colliculus projections to target populations in the supraoculomotor area of the macaque monkey.Visual neuroscience · 2021Article
- Pupil Size as a Window on Neural Substrates of Cognition.Trends in cognitive sciences · 2020Review
- Both a Gauge and a Filter: Cognitive Modulations of Pupil Size.Frontiers in neurology · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Spatial attention enables us to focus visual processing toward specific locations or stimuli before the next fixation. Recent evidence has suggested that local luminance at the spatial locus of attention or saccade preparation influences pupil size independent of global luminance levels. However, it remains to be determined which neural pathways produce this location-specific modulation of pupil size. The intermediate layers of the midbrain superior colliculus (SC) form part of the network of brain areas involved in spatial attention and modulation of pupil size. Here, we demonstrated that pupil size was altered according to local luminance level at the spatial location corresponding to a microstimulated location in the intermediate SC (SCi) map of monkeys. Moreover, local SCi inactivation through injection of lidocaine reversed this local luminance modulation. Our findings reveal a causal role of the SCi in preparing pupil size for local luminance conditions at the next saccadic goal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.