Evidence map›Paper›PMID 30249634›Full record

ArticleThe Plant cell2018

Trehalose 6-Phosphate Positively Regulates Fatty Acid Synthesis by Stabilizing WRINKLED1.

Zhiyang Zhai, Jantana Keereetaweep, Hui Liu, Regina Feil, John E Lunn, John Shanklin

Open access · hybridAbstract read
In one paragraph

Article in The Plant cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed
24.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 214 citations in OpenAlex.

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  11. Cellular energy sensor SnRK1 suppresses salicylic acid-dependent and -independent defenses and bacterial resistance inProceedings of the National Academy of Sciences of the United States of America · 2025
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  17. Sugar-sensing swodkoreceptors and swodkocrine signaling.Animal models and experimental medicine · 2025
    Article
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zhiyang ZhaiDepartment of Biology, Brookhaven National Laboratory, Upton, New York 11973.ORCID 0000-0003-3181-1773
Jantana KeereetaweepDepartment of Biology, Brookhaven National Laboratory, Upton, New York 11973.ORCID 0000-0001-8314-9289
Hui LiuDepartment of Biology, Brookhaven National Laboratory, Upton, New York 11973.ORCID 0000-0001-8524-1759
Regina FeilMax Planck Institute of Molecular Plant Physiology, 14476 Potsdam-Golm, Germany.ORCID 0000-0002-9936-1337
John E LunnMax Planck Institute of Molecular Plant Physiology, 14476 Potsdam-Golm, Germany.ORCID 0000-0001-8533-3004
John ShanklinDepartment of Biology, Brookhaven National Laboratory, Upton, New York 11973 shanklin@bnl.gov.ORCID 0000-0002-6774-8043
Brookhaven National Laboratory · USMax Planck Institute of Molecular Plant Physiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

WRINKLED1 (WRI1), the transcriptional activator of fatty acid synthesis, was recently identified as a target of KIN10, a catalytic α-subunit of the SUCROSE-NON-FERMENTING1-RELATED PROTEIN KINASE1 (SnRK1). We tested the hypothesis that trehalose 6-phosphate (T6P), a signal of cellular sucrose status, can regulate fatty acid synthesis by inhibiting SnRK1. Incubation of

Indexed as

ArabidopsisArabidopsis ProteinsBrassica napusCell Culture TechniquesFatty AcidsGlucosyltransferasesMutationNicotianaPhosphorylationPlant LeavesPlant ProteinsPlants, Genetically ModifiedProtein Serine-Threonine KinasesSugar PhosphatesTranscription FactorsTrehaloseArabidopsis ProteinsAt3g01090 protein, ArabidopsisFatty AcidsGlucosyltransferasesGRIK1 protein, ArabidopsisPlant ProteinsProtein Serine-Threonine KinasesSugar PhosphatesTranscription FactorsTrehalosetrehalose-6-phosphatetrehalose-6-phosphate synthaseWRINKLED1 protein, Arabidopsis

Identifiers

PMID30249634
PMCPMC6241258
OpenAlexW2891141708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.