Evidence map›Paper›PMID 30249631›Full record

Observational studyBMJ open2018

AIDS Therapy Evaluation in the Netherlands (ATHENA) national observational HIV cohort: cohort profile.

Tamara Sonia Boender, Colette Smit, Ard van Sighem, Daniela Bezemer, Catriona J Ester, Sima Zaheri, Ferdinand W N M Wit, Peter Reiss, ATHENA national observational HIV cohort

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Identifying socioeconomic characteristics of pregnant women aged 15-50 years diagnosed with HIV during pregnancy, the Netherlands, 2016 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
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  11. Observational
  12. Impact of Socio-Economic, Behavioural and Clinical Factors on Liver Disease Progression in Individuals With HIV and Hepatitis B.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Observational
  13. Article
  14. Article
  15. Article
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  17. Low coverage of hepatitis D virus testing in individuals with hepatitis B virus and HIV, the Netherlands, 2000 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tamara Sonia BoenderStichting HIV Monitoring, Amsterdam, the Netherlands.ORCID 0000-0002-4418-3713
Colette SmitStichting HIV Monitoring, Amsterdam, the Netherlands.
Ard van SighemStichting HIV Monitoring, Amsterdam, the Netherlands.
Daniela BezemerStichting HIV Monitoring, Amsterdam, the Netherlands.
Catriona J EsterStichting HIV Monitoring, Amsterdam, the Netherlands.
Sima ZaheriStichting HIV Monitoring, Amsterdam, the Netherlands.
Ferdinand W N M WitStichting HIV Monitoring, Amsterdam, the Netherlands.
Peter ReissStichting HIV Monitoring, Amsterdam, the Netherlands.
ATHENA national observational HIV cohort
Stichting HIV Monitoring · NLAmsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn 1998, the AIDS Therapy Evaluation in the Netherlands (ATHENA) national observational HIV cohort was established to demonstrate the lifesaving effectiveness of triple combination antiretroviral therapy, including HIV-protease inhibitors, that had recently been made available for clinical use. Subsequently, the HIV Monitoring Foundation was established by the Dutch Ministry of Health, Welfare and Sport to continue ATHENA as an open cohort in order to continue the registration and monitoring of all HIV-positive people as an integral part of HIV care in all 26 HIV treatment centres in the Netherlands.

participantsTo date, a total of 25 036 participants have been enrolled in the cohort, with 263 600 person-years of follow-up. As of 1 January 2017, 19 035 HIV-1-positive participants were known to be in care: 18 824 adults (81% men and 19% women) and 211 children (47% boys and 53% girls). The remaining 6001 participants had either died (46%), were lost to care (29%) or had moved abroad (25%). FINDINGS TO DATE: Today, with over 20 years of follow-up, the ATHENA cohort has provided extensive knowledge on HIV treatment, comorbidities and coinfections and created insight into the transmission dynamics of the HIV epidemic. FUTURE PLANS: ATHENA continues to enrol and monitor HIV positive people entering HIV care in the Netherlands. Future research will continue to provide tangible input into HIV care and prevention policies in the Netherlands and internationally.

Indexed as

Antiretroviral Therapy, Highly ActiveDrug MonitoringHIV InfectionsPatient Care ManagementAdultChildCohort StudiesFemaleHumansMaleNetherlandsOutcome and Process Assessment, Health CareTreatment OutcomeepidemiologyHIV & AIDSinfectious diseasespublic healthvirology

Identifiers

PMID30249631
PMCPMC6169757
OpenAlexW2891129221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.