Evidence map›Paper›PMID 30249612›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2018

Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care.

Francis Nissen, Daniel R Morales, Hana Mullerova, Liam Smeeth, Ian J Douglas, Jennifer K Quint

Abstract readValidation Study
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. GOLD 2021 Strategy Report: Implications for Asthma-COPD Overlap.International journal of chronic obstructive pulmonary disease · 2021
    Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francis NissenDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London.
Daniel R MoralesDivision of Population Health Sciences, University of Dundee, Dundee.
Hana MullerovaReal World Data and Epidemiology, GlaxoSmithKline Research and Development, Uxbridge.
Liam SmeethDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London.
Ian J DouglasDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London.
Jennifer K QuintNational Heart and Lung Institute, Imperial College, London.

Funding

Medical Research Council G0802403
6 · The paper itself

Abstract

backgroundAsthma and chronic obstructive pulmonary disease (COPD) share many characteristics and symptoms, and the differential diagnosis between the two diseases can be difficult in primary care. This study explored potential overlap between both diseases in a primary care environment.

aimTo quantify how commonly patients with COPD have a concomitant diagnosis of asthma, and how commonly patients with asthma have a concomitant diagnosis of COPD in UK primary care. Additionally, the study aimed to determine the extent of possible misdiagnosis and missed opportunities for diagnosis. DESIGN AND

settingPatients with validated asthma and patients with validated COPD in primary care were identified from the UK Clinical Practice Research Datalink (CPRD) in separate validation studies, and the diseases were confirmed by review of GP questionnaires.

methodThe prevalence of concurrent asthma and COPD in validated cases of either disease was examined based on CPRD coding, GP questionnaires, and requested additional information.

resultsIn total, 400 patients with COPD and 351 patients with asthma in primary care were identified. Of the patients with validated asthma, 15% (

conclusionA concurrent asthma and COPD diagnosis appears to affect a relative minority of patients with COPD (14.5%) or asthma (14.8%). Asthma diagnosis may be over-recorded in people with COPD.

Indexed as

Primary Health CareAdultAgedAsthmaClinical CodingDatabases, FactualDiagnosis, DifferentialDiagnostic ErrorsFemaleHumansMaleMiddle AgedPractice Patterns, Physicians'Pulmonary Disease, Chronic ObstructiveQualitative ResearchReferral and ConsultationasthmaCOPDelectronic health recordsepidemiologyprimary health carevalidation studies

Identifiers

PMID30249612
PMCPMC6193792

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.