Evidence map›Paper›PMID 30249603›Full record

ReviewThe EMBO journal2018

Postsynaptic localization and regulation of AMPA receptors and Cav1.2 by β2 adrenergic receptor/PKA and Ca

Tommaso Patriarchi, Olivia R Buonarati, Johannes W Hell

Abstract readReview
In one paragraph

Review in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. R-type voltage-gated CaCell reports · 2022
    Article
  20. Role of CaFrontiers in molecular neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tommaso PatriarchiDepartment of Pharmacology, University of California, Davis, CA, USA.
Olivia R BuonaratiDepartment of Pharmacology, University of California, Davis, CA, USA.
Johannes W HellDepartment of Pharmacology, University of California, Davis, CA, USA jwhell@ucdavis.edu.ORCID 0000-0001-7960-7531

Funding

Role of a-actinin in Cav1.2 FunctionR01AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2016 to 2026
$4.0M
Molecular Mechanisms of Postsynaptic AMPA Receptor LocalizationR01MH097887 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2014 to 2018
$2.5M
Signaling by cAMP within postsynaptic nano domains R01NS078792R01NS078792 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2016
$2.0M
NIA NIH HHS R01 AG055357NIMH NIH HHS R01 MH097887NINDS NIH HHS R01 NS078792
6 · The paper itself

Abstract

The synapse transmits, processes, and stores data within its tiny space. Effective and specific signaling requires precise alignment of the relevant components. This review examines current insights into mechanisms of AMPAR and NMDAR localization by PSD-95 and their spatial distribution at postsynaptic sites to illuminate the structural and functional framework of postsynaptic signaling. It subsequently delineates how β

Indexed as

AnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium Channels, L-TypeCalcium SignalingCyclic AMP-Dependent Protein KinasesHumansReceptors, Adrenergic, beta-2Receptors, AMPAReceptors, N-Methyl-D-AspartateSynapsesCACNA1C protein, humanCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium Channels, L-TypeCyclic AMP-Dependent Protein KinasesReceptors, Adrenergic, beta-2Receptors, AMPAReceptors, N-Methyl-D-AspartateAKAPcAMPNMDA receptorsnorepinephrinePSD‐95

Identifiers

PMID30249603
PMCPMC6187224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.