Evidence map›Paper›PMID 30249402›Full record

ArticleBiophysical journal2018

Insights into the Cooperative Nature of ATP Hydrolysis in Actin Filaments.

Harshwardhan H Katkar, Aram Davtyan, Aleksander E P Durumeric, Glen M Hocky, Anthony C Schramm, Enrique M De La Cruz, Gregory A Voth

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Journal of chemical theory and computation · 2023
    Article
  3. OpenMSCG: A Software Tool for Bottom-Up Coarse-Graining.The journal of physical chemistry. B · 2023
    Article
  4. Article
  5. Article
  6. Bottom-up Coarse-Graining: Principles and Perspectives.Journal of chemical theory and computation · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Structural basis for polarized elongation of actin filaments.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. Temperature and Phase Transferable Bottom-up Coarse-Grained Models.Journal of chemical theory and computation · 2020
    Article
  13. Article
  14. Charge-dependent interactions of monomeric and filamentous actin with lipid bilayers.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Advances in coarse-grained modeling of macromolecular complexes.Current opinion in structural biology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Harshwardhan H KatkarDepartment of Chemistry, Institute for Biophysical Dynamics and James Frank Institute, University of Chicago, Chicago, Illinois.
Aram DavtyanDepartment of Chemistry, Institute for Biophysical Dynamics and James Frank Institute, University of Chicago, Chicago, Illinois.
Aleksander E P DurumericDepartment of Chemistry, Institute for Biophysical Dynamics and James Frank Institute, University of Chicago, Chicago, Illinois.
Glen M HockyDepartment of Chemistry, Institute for Biophysical Dynamics and James Frank Institute, University of Chicago, Chicago, Illinois.
Anthony C SchrammDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut.
Enrique M De La CruzDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut.
Gregory A VothDepartment of Chemistry, Institute for Biophysical Dynamics and James Frank Institute, University of Chicago, Chicago, Illinois. Electronic address: gavoth@uchicago.edu.
University of Chicago · USYale University · US

Funding

Actin filament elasticity and actin-binding protein functionR01GM097348 · NIGMS · YALE UNIVERSITY · PI DE LA CRUZ, ENRIQUE M · 2011 to 2018
$3.1M
NIGMS NIH HHS R01 GM097348
6 · The paper itself

Abstract

Actin filaments continually assemble and disassemble within a cell. Assembled filaments "age" as a bound nucleotide ATP within each actin subunit quickly hydrolyzes followed by a slower release of the phosphate P

Indexed as

Actin CytoskeletonActinsAdenosine DiphosphateAdenosine TriphosphateHumansHydrolysisKineticsPhosphatesActinsAdenosine DiphosphateAdenosine TriphosphatePhosphates

Identifiers

PMID30249402
PMCPMC6260209
OpenAlexW2949314358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.