Evidence map›Paper›PMID 30249263›Full record

ArticleCardiovascular ultrasound2018

Left atrium remodeling predicts late recurrence of paroxysmal atrial fibrillation after second generation cryoballoon ablation.

Andreea Motoc, Juan-Pablo Abugattas, Bram Roosens, Esther Scheirlynck, Benedicte Heyndrickx, Carlo de Asmundis, Gian-Battista Chierchia, Steven Droogmans, Bernard Cosyns

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular ultrasound, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Andreea MotocCentrum Voor Hart-en Vaatziekten (CHVZ), Department of Cardiology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium. andreea.motoc@gmail.com.ORCID http://orcid.org/0000-0002-9168-2398
Juan-Pablo AbugattasHeart Rhythm Management Centre, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Bram RoosensCentrum Voor Hart-en Vaatziekten (CHVZ), Department of Cardiology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Esther ScheirlynckCentrum Voor Hart-en Vaatziekten (CHVZ), Department of Cardiology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Benedicte HeyndrickxCentrum Voor Hart-en Vaatziekten (CHVZ), Department of Cardiology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Carlo de AsmundisHeart Rhythm Management Centre, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Gian-Battista ChierchiaHeart Rhythm Management Centre, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Steven DroogmansCentrum Voor Hart-en Vaatziekten (CHVZ), Department of Cardiology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Bernard CosynsCentrum Voor Hart-en Vaatziekten (CHVZ), Department of Cardiology, UZ Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Universitair Ziekenhuis Brussel · BEMathys (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is the most common arrhythmia worldwide. Nowadays, AF ablation is a valuable treatment option. It has been shown that the left atrium (LA) diameter is a predictor of AF recurrence after cryoballoon ablation (CBA). Since it does not reflect the true LA size, we compared the role of different LA anatomical parameters using echocardiography for the prediction of AF recurrence after CBA.

methodsWe retrospectively included 209 patients (mean age 56.1 ± 13.6 years, male 62%) with paroxysmal AF undergoing CBA. A transthoracic echocardiography was performed in all patients.

resultsAt a mean follow-up of 16.9 ± 6.3 months, AF recurred in 25.4% of the patients. LA anterior - posterior diameter (LAD), LA minimum volume (LAmin) and early AF recurrence were independent predictors of recurrence. Based on receiver operating characteristics, cut - off values for LAD and, LAmin were 41 mm, 23.69 mL, respectively. The negative predictive values for recurrence were 73% and 87.3% respectively. In patients with AF recurrence, a significant proportion (30.2%) showed LA longitudinal remodeling (LA superior - inferior diameter) even though classically measured LAD was normal.

conclusionsLongitudinal LA remodeling plays an additional role for predicting AF recurrence after CBA, in patients without LAD dilation. Moreover, LAmin had a high negative predictive value and was an independent predictor of AF recurrence. Therefore, a more complete LA anatomical assessment allows a better prediction of AF recurrences after CBA.

Indexed as

Atrial RemodelingAtrial FibrillationCatheter AblationEchocardiographyEquipment DesignFemaleHeart AtriaHumansMaleMiddle AgedPrognosisRecurrenceRetrospective StudiesROC CurveTachycardia, ParoxysmalTreatment OutcomeAtrial fibrillationCryoballoon ablationEchocardiographyLeft atrium

Identifiers

PMID30249263
PMCPMC6154403
OpenAlexW2886042124

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.