ArticleCardiovascular ultrasound2018
Relation of arterial stiffness to left ventricular structure and function in healthy women.
Article in Cardiovascular ultrasound, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Article
- Two-dimensional speckle tracking of the ascending aorta: a novel approach to evaluate arterial stiffness in pediatric patients with repaired conotruncal anomalies using echocardiography.Frontiers in cardiovascular medicine · 2025Article
- Biventricular interaction and aortic function in adult patients with repaired tetralogy of Fallot: a two-dimensional-three-dimensional speckle-tracking echocardiographic study.European heart journal. Imaging methods and practice · 2024Article
- Current Insights into the Significance of the Renal Resistive Index in Kidney and Cardiovascular Disease.Diagnostics (Basel, Switzerland) · 2023Review
- Determinants of Arterial Stiffness in Patients with Morbid Obesity. The Role of Echocardiography and Carotid Ultrasound Imaging.Medicina (Kaunas, Lithuania) · 2023Article
- Clinical Applications Measuring Arterial Stiffness: An Expert Consensus for the Application of Cardio-Ankle Vascular Index.American journal of hypertension · 2022Article
- Left ventricular rotational abnormalities in adult patients with corrected tetralogy of Fallot following different surgical procedures (Results from the CSONGRAD Registry and MAGYAR-Path Study).Cardiovascular diagnosis and therapy · 2021Article
- Left ventricular strains correlate with aortic elastic properties in adult patients with corrected tetralogy of Fallot (Results from the CSONGRAD Registry and MAGYAR-Path Study).Cardiovascular diagnosis and therapy · 2021Article
- Persistent Aortic Stiffness and Left Ventricular Hypertrophy in Children of Diabetic Mothers.CJC open · 2021Article
- Characterization of Cardiac, Vascular, and Metabolic Changes in Young Childhood Cancer Survivors.Frontiers in pediatrics · 2021Article
- Review
- RNA-sequencing analysis of differential gene expression associated with arterial stiffness.Vascular · 2020Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundInteractions between the left ventricular (LV) and the arterial system, (ventricular-arterial coupling) are key determinants of cardiovascular function. However, most of studies covered multiple cardiovascular risk factors, which also contributed to the morphological and functional changes of LV. The aim of this study was to examine the relationship between arterial stiffness and LV structure and function in healthy women with a low burden of risk factors.
methodsHealthy women from the Twins UK cohort (n = 147, mean age was 54.07 ± 11.90 years) were studied. Arterial stiffness was evaluated by carotid-femoral pulse wave velocity (cf-PWV). LV structure and function were assessed by two-dimensional speckle tracking echocardiography.
resultscf-PWV was significantly associated with most measures of LV geometry and function, including relative wall thickness (RWT), E/e' ratio, global circumferential and radial strain, apical rotation and LV twist (each p < 0.05), but bore no relation to global longitudinal strain. After adjustment for age, body mass index, blood pressure and heart rate, cf-PWV was significantly correlated with RWT, global circumferential strain, apical rotation and LV twist (β = 0.011, - 0.484, 1.167 and 1.089, respectively, each p ≤ 0.05).
conclusionsIn healthy women with a low burden of risk factors, elevated arterial stiffness was intimately interwoven with increased LV twisting even before LV dysfunction becomes clinically evident.
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