Evidence map›Paper›PMID 30249203›Full record

ArticleBMC family practice2018

Rationale and design of a pragmatic clinical trial to assess the impact of self-monitoring blood pressure at home and self-titration of antihypertensive medication in poorly controlled hypertension: the ADAMPA study protocol.

José Sanfélix-Genovés, Clara L Rodríguez-Bernal, Irene Marco-Moreno, Patricia Martinez-Ibañez, Lucía Martinez-Ibañez, María Bóveda-García, Ignacio Barreira-Franch, Mercedes Calleja-Del Ser, Greta Borrás-Moreno, Eugenia Avelino-Hidalgo and 8 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC family practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

José Sanfélix-GenovésCentro de Salud de Nazaret, Departamento de Salud de Valencia Clínic-La Malvarrosa, Valencia, Spain. sanfelix_jos@gva.es.
Clara L Rodríguez-BernalHealth Services Research Unit, FISABIO, Valencia, Spain.
Irene Marco-MorenoHealth Research Institute (INCLIVA), Valencia, Spain.
Patricia Martinez-IbañezHealth Research Institute (INCLIVA), Valencia, Spain.
Lucía Martinez-IbañezHealth Research Institute (INCLIVA), Valencia, Spain.
María Bóveda-GarcíaHealth Research Institute (INCLIVA), Valencia, Spain.
Ignacio Barreira-FranchHealth Research Institute (INCLIVA), Valencia, Spain.
Mercedes Calleja-Del SerHealth Research Institute (INCLIVA), Valencia, Spain.
Greta Borrás-MorenoHealth Research Institute (INCLIVA), Valencia, Spain.
Eugenia Avelino-HidalgoHealth Research Institute (INCLIVA), Valencia, Spain.
Marina Escrig-VesesHealth Research Institute (INCLIVA), Valencia, Spain.
Margherita LaurianoHealth Research Institute (INCLIVA), Valencia, Spain.
Margarita Giménez-LoreiroHealth Research Institute (INCLIVA), Valencia, Spain.
Laura Bellot-PujalteHealth Research Institute (INCLIVA), Valencia, Spain.
Aníbal García-SempereHealth Services Research Unit, FISABIO, Valencia, Spain.
Salvador PeiróHealth Services Research Unit, FISABIO, Valencia, Spain.
Gabriel Sanfélix-GimenoHealth Services Research Unit, FISABIO, Valencia, Spain.
ADAMPA group
INCLIVA Health Research Institute · ESFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESDepartamento de Salud · ESSpanish Clinical Research Network · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLack of control of hypertension is one of the most prevalent problems encountered by general practitioners (GPs). Self-measured blood pressure monitoring at home (SMBP) and self-titration of medication could be a good strategy to improve hypertension management, however, evidence is limited and not conclusive. We aimed to assess the effectiveness, in the primary care setting, of an intervention that includes educational components, SMBP and self-titration of antihypertensive medication to decrease systolic blood pressure compared to usual care, in a population with poorly controlled hypertension, during a 12-month period.

methodsPragmatic, controlled, randomized, unblinded clinical trial with two parallel groups assigned in a ratio of 1:1 to self-management (which includes educational components, SBMP and self-titration of antihypertensive medication based on a patient's GP's pre-established adjustment plan) or to usual care (with educational components too). DISCUSSION: If the data from this trial show positive results, the study may contribute to a change of strategy in the treatment of hypertension, focusing on the patient as the main actor to achieve blood pressure control. Furthermore, this approach might contribute to the financial sustainability of the National Health Service.

trial registrationThis trial has been registered in the database with reference number EudraCT: 2016-003986-25. Registered 05 May 2017, https://www.clinicaltrialsregister.eu/ctr-search/search?query=2016-003986-25.

Indexed as

Antihypertensive AgentsBlood Pressure Monitoring, AmbulatoryHypertensionSelf CareBlood Pressure DeterminationHumansPragmatic Clinical Trials as TopicSpainAntihypertensive AgentsBlood pressureHypertensionPragmatic clinical trialPrimary careSelf-monitoringSelf-titration

Identifiers

PMID30249203
PMCPMC6154875
OpenAlexW2890365289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.