Evidence map›Paper›PMID 30249048›Full record

ArticleViruses2018

Viruses.STRING: A Virus-Host Protein-Protein Interaction Database.

Helen Victoria Cook, Nadezhda Tsankova Doncheva, Damian Szklarczyk, Christian von Mering, Lars Juhl Jensen

Abstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Review
  2. Review
  3. Identification of Virus-Host Interactions.Advances in experimental medicine and biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Computational function prediction of bacteria and phage proteins.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Cat-E: A comprehensive web tool for exploring cancer targeting strategies.Computational and structural biotechnology journal · 2024
    Article
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Helen Victoria CookNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen N, Danmark. helen.cook@gmail.com.ORCID 0000-0002-2659-3727
Nadezhda Tsankova DonchevaNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen N, Danmark. nadezhda.doncheva@cpr.ku.dk.ORCID 0000-0002-8806-6850
Damian SzklarczykSwiss Institute of Bioinformatics, University of Zurich, 8006 Zurich, Switzerland. damian.szklarczyk@imls.uzh.ch.
Christian von MeringSwiss Institute of Bioinformatics, University of Zurich, 8006 Zurich, Switzerland. mering@imls.uzh.ch.
Lars Juhl JensenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen N, Danmark. lars.juhl.jensen@cpr.ku.dk.ORCID 0000-0001-7885-715X

Funding

Novo Nordisk NNF14CC0001
6 · The paper itself

Abstract

As viruses continue to pose risks to global health, having a better understanding of virus⁻host protein⁻protein interactions aids in the development of treatments and vaccines. Here, we introduce Viruses.STRING, a protein⁻protein interaction database specifically catering to virus⁻virus and virus⁻host interactions. This database combines evidence from experimental and text-mining channels to provide combined probabilities for interactions between viral and host proteins. The database contains 177,425 interactions between 239 viruses and 319 hosts. The database is publicly available at viruses.string-db.org, and the interaction data can also be accessed through the latest version of the Cytoscape STRING app.

Indexed as

Databases, ProteinHost-Pathogen InteractionsProtein Interaction MappingAnimalsGene OntologyHumansProbabilityProtein BindingProtein Interaction MapsProteinsSoftware DesignVirusesProteinsPPI databaseprotein–protein interactionsvirus bioinformaticsvirus–host interactions

Identifiers

PMID30249048
PMCPMC6213343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.