Evidence map›Paper›PMID 30249041›Full record

ArticleSensors (Basel, Switzerland)2018

Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips.

Zdeněk Pilát, Martin Kizovský, Jan Ježek, Stanislav Krátký, Jaroslav Sobota, Martin Šiler, Ota Samek, Tomáš Buryška, Pavel Vaňáček, Jiří Damborský and 2 more

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Zdeněk PilátInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. pilat@isibrno.cz.ORCID 0000-0001-9259-8393
Martin KizovskýInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. martink@isibrno.cz.
Jan JežekInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. jezek@isibrno.cz.
Stanislav KrátkýInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. kratky@isibrno.cz.
Jaroslav SobotaInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. sobota@isibrno.cz.
Martin ŠilerInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. siler@isibrno.cz.ORCID 0000-0001-9040-4735
Ota SamekInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. osamek@isibrno.cz.
Tomáš BuryškaLoschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 62500 Brno, Czech Republic. bary@mail.muni.cz.
Pavel VaňáčekLoschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 62500 Brno, Czech Republic. PavelVanacek@seznam.cz.
Jiří DamborskýLoschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 62500 Brno, Czech Republic. jiri@chemi.muni.cz.ORCID 0000-0002-7848-8216
Zbyněk ProkopLoschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 62500 Brno, Czech Republic. zbynek@chemi.muni.cz.
Pavel ZemánekInstitute of Scientific Instruments of the CAS, v.v.i., Czech Academy of Sciences, Kralovopolska 147, 61264 Brno, Czech Republic. pavlik@isibrno.cz.
Czech Academy of Sciences, Institute of Scientific Instruments · CZMasaryk University · CZ

Funding

European Commission CZ.1.05/2.1.00/01.0017Grantová Agentura České Republiky 16-07965SMinisterstvo Školství, Mládeže a Tělovýchovy LM2015051Ministerstvo Školství, Mládeže a Tělovýchovy LO1212Ministerstvo Školství, Mládeže a Tělovýchovy LO1214
6 · The paper itself

Abstract

Optofluidics, a research discipline combining optics with microfluidics, currently aspires to revolutionize the analysis of biological and chemical samples, e.g., for medicine, pharmacology, or molecular biology. In order to detect low concentrations of analytes in water, we have developed an optofluidic device containing a nanostructured substrate for surface enhanced Raman spectroscopy (SERS). The geometry of the gold surface allows localized plasmon oscillations to give rise to the SERS effect, in which the Raman spectral lines are intensified by the interaction of the plasmonic field with the electrons in the molecular bonds. The SERS substrate was enclosed in a microfluidic system, which allowed transport and precise mixing of the analyzed fluids, while preventing contamination or abrasion of the highly sensitive substrate. To illustrate its practical use, we employed the device for quantitative detection of persistent environmental pollutant 1,2,3-trichloropropane in water in submillimolar concentrations. The developed sensor allows fast and simple quantification of halogenated compounds and it will contribute towards the environmental monitoring and enzymology experiments with engineered haloalkane dehalogenase enzymes.

Indexed as

1,2,3-trichloropropanechloroalkaneKlarite 312microfluidicssurface enhanced Raman spectroscopy

Identifiers

PMID30249041
PMCPMC6210807
OpenAlexW2893039386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.