Evidence map›Paper›PMID 30249028›Full record

ArticleMarine drugs2018

Marine Peroxy Sesquiterpenoids Induce Apoptosis by Modulation of Nrf2-ARE Signaling in HCT116 Colon Cancer Cells.

Junsei Taira, Haruna Miyazato, Katsuhiro Ueda

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Wound-Healing Efficacy ofPharmaceuticals (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Junsei TairaDepartment Bioresource Technology, Okinawa National College of Technology, 905 Henoko, Nago-city Okinawa Prefecture 905-2192, Japan. taira@okinawa-ct.ac.jp.
Haruna MiyazatoDepartment Bioresource Technology, Okinawa National College of Technology, 905 Henoko, Nago-city Okinawa Prefecture 905-2192, Japan. miyazato@gmail.com.
Katsuhiro UedaDepartment of Chemistry, Biology and Marine Science, University of the Ryukyus, 1 Senbaru, Nishihara-cho, Okinawa 903-2013, Japan. kueda@sci.u-ryukyu.ac.jp.
National Institute of Technology Okinawa College · JPUniversity of the Ryukyus · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our current study demonstrated that the marine peroxy sesquiterpenoids isolated from the Okinawan soft coral

Indexed as

AnthozoaAnimalsAntineoplastic AgentsAntioxidant Response ElementsApoptosisApoptosis Regulatory ProteinsColonic NeoplasmsDrug Screening Assays, AntitumorHCT116 CellsHumansHydrogen PeroxideNF-E2-Related Factor 2Oxidative StressSesquiterpenesSignal TransductionAntineoplastic AgentsApoptosis Regulatory ProteinsHydrogen PeroxideNFE2L2 protein, humanNF-E2-Related Factor 2Sesquiterpenesapoptosisfree radicalHCT116 colon cancer cellsNrf2-ARE signalingperoxy sesquiterpenoidSinularia sp.soft coral

Identifiers

PMID30249028
PMCPMC6213732
OpenAlexW2889990981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.