ArticleSensors (Basel, Switzerland)2018
Noninvasive Glucose Monitoring with a Contact Lens and Smartphone.
Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 82 citations in OpenAlex.
- Evolution of Biosensors and Current State-of-the-Art Applications in Diabetes Control.Biosensors · 2026Review
- A Linear and High-Sensitivity Microwave Biosensor on a FR-4 Substrate for Aqueous Glucose Monitoring Using a Concentric Square-Shaped Split-Ring Resonator.Sensors (Basel, Switzerland) · 2025Article
- Wearable Electrochemical Glucose Sensors for Fluid Monitoring: Advances and Challenges in Non-Invasive and Minimally Invasive Technologies.Biosensors · 2025Review
- Smart Contact Lenses in Ophthalmology: Innovations, Applications, and Future Prospects.Micromachines · 2024Review
- Noninvasive Glucose Sensing In Vivo.Sensors (Basel, Switzerland) · 2023Review
- [Research progress on minimally invasive and non-invasive blood glucose detection methods].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- Reshaping healthcare with wearable biosensors.Scientific reports · 2023Article
- Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing.Scientific reports · 2022Article
- A Review of Digital Health and Biotelemetry: Modern Approaches towards Personalized Medicine and Remote Health Assessment.Journal of personalized medicine · 2022Review
- Wireless Non-Invasive Monitoring of Cholesterol Using a Smart Contact Lens.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Metal-Organic Enzyme Nanogels as Nanointegrated Self-Reporting Chemobiosensors.ACS applied materials & interfaces · 2022Article
- Lab-on-a-Contact Lens: Recent Advances and Future Opportunities in Diagnostics and Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2022Review
- Recent Advancement in Biofluid-Based Glucose Sensors Using Invasive, Minimally Invasive, and Non-Invasive Technologies: A Review.Nanomaterials (Basel, Switzerland) · 2022Review
- Noncontact Optical Measurement of Aqueous Humor Glucose Levels and Correlation with Serum Glucose Levels in Rabbit.Biosensors · 2021Article
- Continuous Non-Invasive Glucose Monitoring via Contact Lenses: Current Approaches and Future Perspectives.Biosensors · 2021Article
- Smart contact lens and transparent heat patch for remote monitoring and therapy of chronic ocular surface inflammation using mobiles.Science advances · 2021Article
- The Application of Wearable Glucose Sensors in Point-of-Care Testing.Frontiers in bioengineering and biotechnology · 2021Review
- Flexible Biosensors Based on Colorimetry, Fluorescence, and Electrochemistry for Point-of-Care Testing.Frontiers in bioengineering and biotechnology · 2021Review
- Advances in Biosensors for Continuous Glucose Monitoring Towards Wearables.Frontiers in bioengineering and biotechnology · 2021Review
- Developing Medical Affairs Leaders Who Create the Future.Pharmaceutical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Diabetes has become a chronic metabolic disorder, and the growing diabetes population makes medical care more important. We investigated using a portable and noninvasive contact lens as an ideal sensor for diabetes patients whose tear fluid contains glucose. The key feature is the reversible covalent interaction between boronic acid and glucose, which can provide a noninvasive glucose sensor for diabetes patients. We present a phenylboronic acid (PBA)-based HEMA contact lens that exhibits a reversible swelling/shrinking effect to change its thickness. The difference in thickness can be detected in a picture taken with a smartphone and analyzed using software. Our novel technique offers the following capabilities: (i) non-enzymatic and continuous glucose detection with the contact lens; (ii) no need for an embedded circuit and power source for the glucose sensor; and (iii) the use of a smartphone to detect the change in thickness of the contact lens with no need for additional photo-sensors. This technique is promising for a noninvasive measurement of the glucose level and simple implementation of glucose sensing with a smartphone.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.