Evidence map›Paper›PMID 30249017›Full record

ArticleInternational journal of molecular sciences2018

Chih-Cheng Chen, Bo-Ching He, Yao-Li Chen, Kuan-Der Lee, Chun-Hsin Tung, Chia-Chen Hsu, Ping-Yi Lin, Pei-Yi Chu, Yu-Wei Leu, Wei-En Fu and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review.Journal of experimental & clinical cancer research : CR · 2019
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chih-Cheng ChenDepartment of Hematology and Oncology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan. ccchen1968@gmail.com.
Bo-Ching HeNano and Mechanical Measurement Laboratory, Center for Measurement Standards, Industrial Technology Research Institute, HsinChu 31057, Taiwan. hopc@itri.org.tw.ORCID 0000-0001-9075-3484
Yao-Li ChenTransplant Medicine & Surgery Research Centre, Changhua Christian Hospital, Changhua 50006, Taiwan. 31560@cch.org.tw.
Kuan-Der LeeDivision of Hematology and Oncology, Department of Medicine, Taipei Medical University Hospital, Taipei 11050, Taiwan. kdlee1964@gmail.com.
Chun-Hsin TungHuman Epigenomics Center, Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, National Chung Cheng University, Chiayi 62102, Taiwan. chun.hsin.tung@gmail.com.
Chia-Chen HsuDepartment of Hematology and Oncology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan. loofahhsu@gmail.com.
Ping-Yi LinTransplant Medicine & Surgery Research Centre, Changhua Christian Hospital, Changhua 50006, Taiwan. 69221@cch.org.tw.
Pei-Yi ChuDepartment of Pathology, Show Chwan Memorial Hospital, Changhua 50008, Taiwan. chu.peiyi@msa.hinet.net.
Yu-Wei LeuHuman Epigenomics Center, Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, National Chung Cheng University, Chiayi 62102, Taiwan. bioywl@ccu.edu.tw.
Wei-En FuNano and Mechanical Measurement Laboratory, Center for Measurement Standards, Industrial Technology Research Institute, HsinChu 31057, Taiwan. weienfu@itri.org.tw.
Shu-Huei HsiaoHuman Epigenomics Center, Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, National Chung Cheng University, Chiayi 62102, Taiwan. bioshh@ccu.edu.tw.

Funding

Chang Gung Memorial Hospital CMRPG6F-0092 and CMRPG6H0321Ministry of Science and Technology, Taiwan 105-2314-B-194 -001Ministry of Science and Technology, Taiwan 107-2320-B-194-002 and 106-2320-B-194 -001 -MY3National Health Research Institutes NHRI-EX102-10259NI
6 · The paper itself

Abstract

Cell stiffness is a potential biomarker for monitoring cellular transformation, metastasis, and drug resistance development. Environmental factors relayed into the cell may result in formation of inheritable markers (e.g., DNA methylation), which provide selectable advantages (e.g., tumor development-favoring changes in cell stiffness). We previously demonstrated that targeted methylation of two tumor suppressor genes, hypermethylated in cancer 1 (

Indexed as

DNA MethylationAnimalsApoptosisBiomarkers, TumorCell MovementCell ProliferationCell Transformation, NeoplasticHumansKruppel-Like Transcription FactorsLiver NeoplasmsMesenchymal Stem CellsMiceMice, NudePrognosisPromoter Regions, GeneticStress, MechanicalBiomarkers, TumorHIC1 protein, humanKruppel-Like Transcription FactorsRASSF1 protein, humanTubulinTumor Suppressor ProteinsAFMcancerDNA methylationstiffness

Identifiers

PMID30249017
PMCPMC6212922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.