Evidence map›Paper›PMID 30248977›Full record

ReviewInternational journal of molecular sciences2018

The Multifaceted Role of Pectin Methylesterase Inhibitors (PMEIs).

Alexandra Wormit, Björn Usadel

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed
21.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 257 citations in OpenAlex.

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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alexandra WormitInstitute of Biology 1, Botany and Molecular Genetics, RWTH Aachen University, 52074 Aachen, Germany. awormit@bio1.rwth-aachen.de.
Björn UsadelInstitute of Biology 1, Botany and Molecular Genetics, RWTH Aachen University, 52074 Aachen, Germany. usadel@bio1.rwth-aachen.de.
Forschungszentrum Jülich · DERWTH Aachen University · DE

Funding

Deutsche Forschungsgemeinschaft US98/113-1
6 · The paper itself

Abstract

Plant cell walls are complex and dynamic structures that play important roles in growth and development, as well as in response to stresses. Pectin is a major polysaccharide of cell walls rich in galacturonic acid (GalA). Homogalacturonan (HG) is considered the most abundant pectic polymer in plant cell walls and is partially methylesterified at the C6 atom of galacturonic acid. Its degree (and pattern) of methylation (DM) has been shown to affect biomechanical properties of the cell wall by making pectin susceptible for enzymatic de-polymerization and enabling gel formation. Pectin methylesterases (PMEs) catalyze the removal of methyl-groups from the HG backbone and their activity is modulated by a family of proteinaceous inhibitors known as pectin methylesterase inhibitors (PMEIs). As such, the interplay between PME and PMEI can be considered as a determinant of cell adhesion, cell wall porosity and elasticity, as well as a source of signaling molecules released upon cell wall stress. This review aims to highlight recent updates in our understanding of the PMEI gene family, their regulation and structure, interaction with PMEs, as well as their function in response to stress and during development.

Indexed as

Carboxylic Ester HydrolasesGene Expression Regulation, PlantPectinsPlant ProteinsCarboxylic Ester HydrolasespectinesterasePectinsPlant Proteinsapplicationscell wall propertiesdegree of methylesterification (DM)developmenthomogalacturonan (HG)pectin methylesterase inhibitor (PMEI), pectinstress

Identifiers

PMID30248977
PMCPMC6213510
OpenAlexW2891015427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.