Evidence map›Paper›PMID 30248918›Full record

ArticleJournal of clinical medicine2018

Effects of the Hormone Replacement Therapy and of Soy Isoflavones on Bone Resorption in Postmenopause.

Delia Mirela Tit, Simona Bungau, Ciprian Iovan, Delia Carmen Nistor Cseppento, Laura Endres, Cristian Sava, Anca Maria Sabau, Gheorghe Furau, Cristian Furau

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Pharmacological Potential ofInternational journal of molecular sciences · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Are Fermented Foods Effective against Inflammatory Diseases?International journal of environmental research and public health · 2023
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Delia Mirela TitDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania. mirela_tit@yahoo.com.ORCID 0000-0002-0296-6592
Simona BungauDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania. simonabungau@gmail.com.ORCID 0000-0003-3236-1292
Ciprian IovanDepartment of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania. dr.iovan@biostandard.ro.
Delia Carmen Nistor CseppentoDepartment of Psycho Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania. delia_cseppento@yahoo.com.
Laura EndresDepartment of Psycho Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania. laura_endres@yahoo.com.ORCID 0000-0002-3315-2364
Cristian SavaDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania. cristian.sava2004@gmail.com.
Anca Maria SabauDepartment of Physical Education, Sport and Physical Therapy, Faculty of Geography, Tourism and Sport, University of Oradea, 410087 Oradea, Romania. sabauancamaria@yahoo.com.
Gheorghe FurauDepartment of Obstetrics and Gynecology, Arad County Clinical Hospital, 310048 Arad, Romania. gfurau@yahoo.com.
Cristian FurauDepartment of Obstetrics and Gynecology, Arad County Clinical Hospital, 310048 Arad, Romania. cristianfurau@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postmenopausal osteoporosis is the most common form of osteoporosis and one of the major public health problems in developed countries. The prevalence of this condition, associated with the physiological stage of menopause, is continuously increasing. This study evaluated the effectiveness of soy isoflavones as compared to hormone replacement therapy (HRT) in low doses, on the prevention of postmenopausal osteoporosis, by determining bone mineral density (BMD) and urinary deoxypyridinoline (D-pyr) in physiological postmenopausal women. The study was conducted over a period of 12 months, on three parallel groups, which included a total of 325 postmenopausal women (HRT group:

Indexed as

BMDbone resorptiondeoxypyridinolineHRTphytoestrogens

Identifiers

PMID30248918
PMCPMC6210155

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.