Evidence map›Paper›PMID 30248888›Full record

ReviewMolecules (Basel, Switzerland)2018

Revisiting Current Photoactive Materials for Antimicrobial Photodynamic Therapy.

Mariana Q Mesquita, Cristina J Dias, Maria G P M S Neves, Adelaide Almeida, M Amparo F Faustino

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 217 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Facile Synthesis of Cu-Doped TiOACS applied engineering materials · 2024
    Article
  8. Mechanism of Action and Efficiency of AgInternational journal of molecular sciences · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Photomodulation Approaches to Overcome Antimicrobial Resistance.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Article
  16. Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Spectroscopic Investigations of Porphyrin-TiOMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mariana Q MesquitaDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal. marianamesquita@ua.pt.
Cristina J DiasDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal. cristina.jesus.dias@ua.pt.
Maria G P M S NevesDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal. gneves@ua.pt.ORCID 0000-0002-7953-8166
Adelaide AlmeidaDepartment of Biology CESAM, University of Aveiro, 3810-193 Aveiro, Portugal. aalmeida@ua.pt.ORCID 0000-0002-8422-8664
M Amparo F FaustinoDepartment of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal. faustino@ua.pt.
University of Aveiro · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial infection is a severe concern, requiring the use of significant amounts of antimicrobials/biocides, not only in the hospital setting, but also in other environments. The increasing use of antimicrobial drugs and the rapid adaptability of microorganisms to these agents, have contributed to a sharp increase of antimicrobial resistance. It is obvious that the development of new strategies to combat planktonic and biofilm-embedded microorganisms is required. Photodynamic inactivation (PDI) is being recognized as an effective method to inactivate a broad spectrum of microorganisms, including those resistant to conventional antimicrobials. In the last few years, the development and biological assessment of new photosensitizers for PDI were accompanied by their immobilization in different supports having in mind the extension of the photodynamic principle to new applications, such as the disinfection of blood, water, and surfaces. In this review, we intended to cover a significant amount of recent work considering a diversity of photosensitizers and supports to achieve an effective photoinactivation. Special attention is devoted to the chemistry behind the preparation of the photomaterials by recurring to extensive examples, illustrating the design strategies. Additionally, we highlighted the biological challenges of each formulation expecting that the compiled information could motivate the development of other effective photoactive materials.

Indexed as

Anti-Bacterial AgentsBacteriaDrug DesignDrug Resistance, BacterialMetal NanoparticlesMolecular StructurePhotochemotherapyPhotosensitizing AgentsAnti-Bacterial AgentsPhotosensitizing Agentsantimicrobial photodynamic therapycellulosechitosandrug deliveryhydrogelsliposomesnanoparticlesnanotubesphotosensitizerssilica

Identifiers

PMID30248888
PMCPMC6222430
OpenAlexW2891810428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.