ArticleLiver international : official journal of the International Association for the Study of the Liver2019
Outcomes after placement of a SX-ELLA oesophageal stent for refractory variceal bleeding-A national multicentre study.
Article in Liver international : official journal of the International Association for the Study of the Liver, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- CROATIAN GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF PORTAL HYPERTENSION.Acta clinica Croatica · 2024Guideline
- Endoscopic management of acute esophagogastric variceal bleeding: recent advances.Therapeutic advances in gastroenterology · 2026Review
- Improved survival in patients with refractory variceal bleeding treated with esophageal stents: A multicenter cohort study.JHEP reports : innovation in hepatology · 2025Article
- Self-Expanding Metal Stents in the Acute Management of Oesophageal Variceal Bleeding: A Systematic Review.Cureus · 2024Review
- Esophageal Stent in Acute Refractory Variceal Bleeding: A Systematic Review and a Meta-Analysis.Journal of clinical medicine · 2024Review
- Austrian consensus on the diagnosis and management of portal hypertension in advanced chronic liver disease (Billroth IV).Wiener klinische Wochenschrift · 2023Article
- Best Practices in Esophageal, Gastroduodenal, and Colonic Stenting.GE Portuguese journal of gastroenterology · 2023Review
- Diagnosis and Management of Esophagogastric Varices.Diagnostics (Basel, Switzerland) · 2023Review
- SX-ELLA Danis-Stent for Refractory Acute Esophageal Variceal Bleeding.GE Portuguese journal of gastroenterology · 2023Article
- Covered Transjugular Intrahepatic Portosystemic Shunt Improves Hypersplenism-Associated Cytopenia in Cirrhosis.Digestive diseases and sciences · 2022Article
- Variceal Bleeding: Beyond Banding.Digestive diseases and sciences · 2022Review
- The role of a novel self-expanding metal stent in variceal bleeding: a multicenter Australian and New Zealand experience.Endoscopy international open · 2022Article
- Clinical algorithms for the prevention of variceal bleeding and rebleeding in patients with liver cirrhosis.World journal of hepatology · 2021Review
- Perceptions on the management of varices and on the use of albumin in patients with cirrhosis among GI specialists in Austria.Wiener klinische Wochenschrift · 2021Article
- Where does TIPS fit in the management of patients with cirrhosis?JHEP reports : innovation in hepatology · 2020Review
- Self-expanding metal stents versus TIPS in treatment of refractory bleeding esophageal varices: a systematic review and meta-analysis.Endoscopy international open · 2020Article
- Impact of farnesoid X receptor single nucleotide polymorphisms on hepatic decompensation and mortality in cirrhotic patients with portal hypertension.Journal of gastroenterology and hepatology · 2019Article
- Biomaterials in Gastroenterology: A Critical Overview.Medicina (Kaunas, Lithuania) · 2019Review
- Outcomes after placement of a SX-ELLA oesophageal stent for refractory variceal bleeding-A national multicentre study.Liver international : official journal of the International Association for the Study of the Liver · 2019Article
Corrections and comments
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Authors and funding
17 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent guidelines favour the use of bleeding stents over balloon tamponade (BT) for refractory variceal bleeding (VB) from oesophageal varices. However, data on the efficacy and safety of self-expandable metal SX-ELLA Danis stents (SEMS) are limited.
methodsCirrhotic patients receiving SEMS for VB at four tertiary care centres were included in this retrospective multicentre study. Rates of failure-to-control bleeding (within 5 days) and bleeding-related mortality (6 weeks) were assessed.
resultsSEMS controlled VB in 79.4% (27/34) of patients. In the rest of patients, other rescue treatments including endoscopic band ligation (EBL, n = 3), SEMS renewed (n = 2) or Linton (n = 2) were applied; however, VB was only controlled in one patient. Early rebleeding within six weeks occurred in 17.6% (6/34) patients. Median SEMS dwell time was three (IQR:6) days. Overall n = 13/34 (38.2%) patients died with SEMS in situ. After SEMS removal, rebleeding and bleeding-related death occurred in n = 7 (35%) and n = 5 (14.7%) patients respectively. Only 32.4% (10/34) patients did not experience any rebleeding within six weeks after SEMS removal. Bleeding-related mortality was 47.1% (n = 16/34) and the median survival after SEMS placement was 2.1 months. Notably, no patient received an early transjugular intrahepatic portosystemic shunt (TIPS). The most common adverse events were stent dislocations (n = 13; 38.2%), while ulcers/necrosis of the oesophageal mucosa was seen in only four (11.8%) patients.
conclusionSEMS controlled refractory VB in most patients. However, bleeding-related mortality remained high. While SEMS dislocations were frequent, ulcers/necrosis of the oesophagus was rare. Further studies should investigate whether the wider use of early TIPS reduces bleeding-related mortality after SEMS placement.
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