Evidence map›Paper›PMID 30247920›Full record

ArticleMolecular pharmaceutics2018

Attenuated Accumulation of Novel Fluorine (

Melissa Metry, Jessica Felton, Kunrong Cheng, Su Xu, Yong Ai, Fengtian Xue, Jean-Pierre Raufman, James E Polli

Abstract readEvaluation Study
In one paragraph

Article in Molecular pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Novel nitroxide-bile acid conjugates inform substrate requirements for human bile acid transporters.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2023
    Article
  2. Review
  3. AMagma (New York, N.Y.) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Melissa MetryDepartment of Pharmaceutical Sciences , University of Maryland School of Pharmacy , Baltimore , Maryland 21201 , United States.
Jessica FeltonDepartment of Surgery , University of Maryland School of Medicine , Baltimore , Maryland 21201 , United States.
Kunrong ChengVA Maryland Healthcare System, and the Department of Medicine, Division of Gastroenterology & Hepatology, and the Marlene and Stewart Greenebaum Comprehensive Cancer Center , University of Maryland School of Medicine , Baltimore , Maryland 21201 , United States.
Su XuDepartment of Diagnostic Radiology and Nuclear Medicine , University of Maryland School of Medicine , Baltimore , Maryland 21201 , United States.
Yong AiDepartment of Pharmaceutical Sciences , University of Maryland School of Pharmacy , Baltimore , Maryland 21201 , United States.
Fengtian XueDepartment of Pharmaceutical Sciences , University of Maryland School of Pharmacy , Baltimore , Maryland 21201 , United States.ORCID 0000-0002-4132-9887
Jean-Pierre RaufmanVA Maryland Healthcare System, and the Department of Medicine, Division of Gastroenterology & Hepatology, and the Marlene and Stewart Greenebaum Comprehensive Cancer Center , University of Maryland School of Medicine , Baltimore , Maryland 21201 , United States.
James E PolliDepartment of Pharmaceutical Sciences , University of Maryland School of Pharmacy , Baltimore , Maryland 21201 , United States.ORCID 0000-0002-5274-4314
University of Maryland, Baltimore · US

Funding

University of Maryland Center of Excellence in Regulatory Science and InnovationU01FD005946 · FDA · UNIV OF MARYLAND, COLLEGE PARK · PI BENTLEY, WILLIAM E., POLLI, JAMES E · 2016 to 2025
$21.5M
Research Training in Gastroenterology and HepatologyT32DK067872 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI RAUFMAN, JEAN-PIERRE · 2005 to 2024
$7.2M
Creating a toolkit to measure in vivo bile acid transportR21DK093406 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI POLLI, JAMES E, RAUFMAN, JEAN-PIERRE · 2012 to 2013
$404k
M3R, MMP1 and Colon Cancer DisseminationI01BX002129 · VA · BALTIMORE VA MEDICAL CENTER · PI RAUFMAN, JEAN-PIERRE · 2015 to 2018
–
BLRD VA I01 BX002129FDA HHS U01 FD005946NIDDK NIH HHS R21 DK093406NIDDK NIH HHS T32 DK067872
6 · The paper itself

Abstract

Our work has focused on defining the utility of fluorine (

Indexed as

AnimalsBile Acids and SaltsDiarrheaDisease Models, AnimalFibroblast Growth FactorsFluorineGallbladderHumansMagnetic Resonance ImagingMaleMiceMice, Inbred C57BLMice, TransgenicMolecular ImagingMolecular ProbesTissue DistributionBile Acids and Saltsfibroblast growth factor 15, mouseFibroblast Growth FactorsFluorineMolecular Probesbile acid diarrheabile acid synthesisenterohepatic circulationFGF15/19fluorine MRIimaging methods

Identifiers

PMID30247920
PMCPMC6446233
OpenAlexW2894267968

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.