ArticleMolecular informatics2019
Data Curation can Improve the Prediction Accuracy of Metabolic Intrinsic Clearance.
Article in Molecular informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Second-Generation Anti-Tubercular Squaramides Targeting Complex V of the Respiratory Chain ofJournal of medicinal chemistry · 2026Article
- Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines.Archives of toxicology · 2026Article
- Data curation in cheminformatics: importance and implementation.Journal of cheminformatics · 2026Review
- Establishing a Pharmacoinformatics Repository of Approved Medicines: A Database to Support Drug Product Development.Molecular pharmaceutics · 2025Article
- The Trends and Future Prospective of In Silico Models from the Viewpoint of ADME Evaluation in Drug Discovery.Pharmaceutics · 2023Review
- Biomedical Ethical Aspects Towards the Implementation of Artificial Intelligence in Medical Education.Medical science educator · 2023Article
- DruMAP: A Novel Drug Metabolism and Pharmacokinetics Analysis Platform.Journal of medicinal chemistry · 2023Article
- Artificial Intelligence in Drug Metabolism and Excretion Prediction: Recent Advances, Challenges, and Future Perspectives.Pharmaceutics · 2023Review
- Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent Glucose Transporter 2 Inhibitor, in Humans.Pharmaceutics · 2023Article
- Computer-Aided (In Silico) Modeling of Cytochrome P450-Mediated Food-Drug Interactions (FDI).International journal of molecular sciences · 2022Review
- FP-ADMET: a compendium of fingerprint-based ADMET prediction models.Journal of cheminformatics · 2021Article
- Metabolic networks of the Nicotiana genus in the spotlight: content, progress and outlook.Briefings in bioinformatics · 2021Article
- Rethinking drug design in the artificial intelligence era.Nature reviews. Drug discovery · 2020Review
- Artificial Intelligence in Drug Discovery: A Comprehensive Review of Data-driven and Machine Learning Approaches.Biotechnology and bioprocess engineering : BBE · 2020Review
- Development of an in silico prediction system of human renal excretion and clearance from chemical structure information incorporating fraction unbound in plasma as a descriptor.Scientific reports · 2019Article
- Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase.PLoS neglected tropical diseases · 2019Article
- Data Curation can Improve the Prediction Accuracy of Metabolic Intrinsic Clearance.Molecular informatics · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A key consideration at the screening stages of drug discovery is in vitro metabolic stability, often measured in human liver microsomes. Computational prediction models can be built using a large quantity of experimental data available from public databases, but these databases typically contain data measured using various protocols in different laboratories, raising the issue of data quality. In this study, we retrieved the intrinsic clearance (CL
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