Evidence map›Paper›PMID 30247238›Full record

ArticleOptometry and vision science : official publication of the American Academy of Optometry2018

Neutralizing Peripheral Refraction Eliminates Refractive Scotomata in Tilted Disc Syndrome.

Jack Phu, Henrietta Wang, Sephora Miao, Lydia Zhou, Sieu K Khuu, Michael Kalloniatis

Open access · greenAbstract read
In one paragraph

Article in Optometry and vision science : official publication of the American Academy of Optometry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Retinoscopes: Past and present.World journal of methodology · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jack PhuCentre for Eye Health, University of New South Wales, Kensington, New South Wales, Australia.
Henrietta WangCentre for Eye Health, University of New South Wales, Kensington, New South Wales, Australia.
Sephora MiaoSchool of Optometry and Vision Science, University of New South Wales, Kensington, New South Wales, Australia *jphu@cfeh.com.au.
Lydia ZhouSchool of Optometry and Vision Science, University of New South Wales, Kensington, New South Wales, Australia *jphu@cfeh.com.au.
Sieu K KhuuSchool of Optometry and Vision Science, University of New South Wales, Kensington, New South Wales, Australia *jphu@cfeh.com.au.
Michael KalloniatisCentre for Eye Health, University of New South Wales, Kensington, New South Wales, Australia.
UNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significanceWe demonstrate that the visual field defects in patients with tilted disc syndrome can be reduced or eliminated by neutralizing the peripheral scotoma in the area of posterior retinal bowing, which may allow differentiation between a congenital anomaly and acquired pathology. PURPOSE: Tilted disc syndrome is a congenital and unchanging condition that may present with visual field defects mimicking loss seen in neurological diseases, such as transsynaptic retrograde degeneration. Our purpose was to systematically investigate the ability of a neutralized peripheral refraction to eliminate refractive visual field defects seen in tilted disc syndrome. This was compared with the same technique performed on patients with neurological deficits.

methodsThe Humphrey Field Analyzer was used to measure sensitivities across the 30-2 test grid in 14 patients with tilted disc syndrome using four refractive corrections: habitual near correction and with an additional -1.00, -2.00 or -3.00 D negative lens added as correction lenses. Peripheral refractive errors along the horizontal meridian were determined using peripheral retinoscopy and thus allowed calculation of residual peripheral refraction with different levels of refractive correction. Visual field defects were assessed qualitatively and quantitatively using sensitivities and probability scores in both patient groups.

resultsA smaller residual refractive error after the application of negative addition lenses correlated with improvement in visual field defects in terms of sensitivity and probability scores in patients with tilted disc syndrome. Patients with established neurological deficits (retrograde degeneration) showed improvement in sensitivities but not in probability scores.

conclusionsNeutralizing the refractive error at the region of posterior retinal bowing due to tilted disc syndrome reduces the apparent visual field defect. This may be a useful and rapid test to help differentiate between tilted disc syndrome and other pathological causes of visual field defects such as neurological deficits.

Indexed as

AdultAgedEye AbnormalitiesFemaleHumansMaleMiddle AgedOphthalmologic Surgical ProceduresOptic DiskProspective StudiesRefraction, OcularRetinoscopyScotomaVision DisordersVisual FieldsVisual Field Tests

Identifiers

PMID30247238
PMCPMC6166693
OpenAlexW2894646457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.