Evidence map›Paper›PMID 30246868›Full record

ArticleClinical and experimental immunology2019

Blood immune cell biomarkers in lung cancer.

D Riemann, M Cwikowski, S Turzer, T Giese, M Grallert, W Schütte, B Seliger

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

D RiemannInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.ORCID 0000-0002-7989-6262
M CwikowskiInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.
S TurzerInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.
T GieseInstitute of Immunology, Heidelberg University Hospital, Germany.
M GrallertDepartment of Thorax Surgery of the Hospital Martha-Maria Halle-Dölau, Halle, Germany.
W SchütteClinic of Internal Medicine, Hospital Martha-Maria Halle-Dölau, Halle, Germany.
B SeligerInstitute of Medical Immunology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Martin Luther University Halle-Wittenberg · DEMartha-Maria Hospital · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characterization of host immune cell parameters prior to treatment is expected to identify biomarkers predictive of clinical outcome as well as to elucidate why some patients fail to respond to immunotherapy. We monitored blood immune cells from 58 patients with non-small- cell lung cancer (NSCLC) undergoing surgery of the primary tumor and from 50 age-matched healthy volunteers. Complete leukocyte blood count, the number of circulating dendritic cells (DC), HLA-DR

Indexed as

AgedBiomarkers, TumorBlood CellsCarcinoma, Non-Small-Cell LungCD4 Lymphocyte CountCD8-Positive T-LymphocytesDendritic CellsFemaleFlow CytometryHLA-DR AntigensHumansKiller Cells, NaturalLung NeoplasmsMaleMiddle AgedMonocytesBiomarkers, TumorHLA-DR Antigensbiomarkerdendritic cellsflow cytometryimmune monitoringlung cancerMDSCnaive T cellsNLRoverall survival

Identifiers

PMID30246868
PMCPMC6330648
OpenAlexW2892571811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.