Evidence map›Paper›PMID 30246613›Full record

ArticleTopics in stroke rehabilitation2018

Improved quality of life following constraint-induced movement therapy is associated with gains in arm use, but not motor improvement.

Kristina M Kelly, Alexandra L Borstad, David Kline, Lynne V Gauthier

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Topics in stroke rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01725919 nacompletednot on this map

Examining Mechanisms of Neuroplasticity Following Motor Rehabilitation in Stroke

TypeinterventionalSponsorOhio State UniversityRan2012 to 2025Enrolled31ConditionsStroke, HemiparesisArmsCI therapy
NCT03005457 nacompletednot on this map

A Low-cost Virtual Reality Gaming Platform for Neurorehabilitation of Hemiparesis

TypeinterventionalSponsorOhio State UniversityRan2012 to 2014Enrolled32ConditionsStroke, Hemiparesis, Upper Extremity DysfunctionArmsHemiparesis Therapy with VR
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Constraint-induced movement therapy protocols using the number of repetitions of task practice: a systematic review of feasibility and effects.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kristina M Kellya Department of Physical Medicine and Rehabilitation , The Ohio State University , Columbus , OH , USA.ORCID 0000-0002-2151-0873
Alexandra L Borstadc Division of Physical Therapy, School of Health and Rehabilitation Sciences , The Ohio State University , Columbus , OH , USA.ORCID 0000-0003-3645-7312
David Klineb Center for Biostatistics , The Ohio State University , Columbus , OH , USA.ORCID 0000-0001-6183-3303
Lynne V Gauthiera Department of Physical Medicine and Rehabilitation , The Ohio State University , Columbus , OH , USA.ORCID 0000-0003-0619-2157
The Ohio State University · US

Funding

The Ohio State University Center for Clinical and Translational Science (UL1)UL1TR000090 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$7.9M
NCATS NIH HHS UL1 TR000090
6 · The paper itself

Abstract

backgroundConstraint-induced movement therapy (CI therapy) is one of few treatments for upper extremity (UE) hemiparesis that has been shown to result in motor recovery and improved quality of life in chronic stroke. However, the extent to which treatment-induced improvements in motor function versus daily use of the more affected arm independently contribute to improved quality of life remains largely unexplored.

objectiveThe objective of this study is to identify whether motor function or daily use of a hemiparetic arm has a greater influence on quality of life after CI therapy.

methodsTwo cohorts of participants with chronic stroke received either in-person CI therapy (n = 29) or video-game home-based CI therapy (n = 16). The two cohorts were combined and the motor-related outcomes (Wolf Motor Function Test, Action Research Arm Test, Motor Activity Log [MAL]) and quality of life (Stroke-Specific Quality of Life) were jointly modeled to assess the associations between outcomes.

resultsThe only outcome associated with improved quality of life was the MAL. Improvements in quality of life were not restricted to motor domains, but generalized to psychosocial domains as well.

conclusionsResults suggest that improved arm use during everyday activities is integral to maximizing quality of life gains during motor rehabilitation for chronic post-stroke UE hemiparesis. In contrast, gains in motor function were not associated with increases in quality of life. These findings further support the need to implement techniques into clinical practice that promote arm use during daily life if improving quality of life is a main goal of treatment. ClinicalTrials.gov Registration Numbers: NCT01725919 and NCT03005457.

Indexed as

Outcome Assessment, Health CareQuality of LifeAdultAgedCohort StudiesExercise Movement TechniquesFemaleHumansMaleMiddle AgedParesisStrokeStroke RehabilitationUpper Extremitybehaviour changechronic strokeConstraint-induced movement therapyhemiparesismotor recoveryquality of lifetransfer package

Identifiers

PMID30246613
PMCPMC6359892
OpenAlexW2893871009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.