Evidence map›Paper›PMID 30246483›Full record

ArticlePediatric transplantation2018

Necrotizing fasciitis caused by Mucor indicus in a pediatric bone marrow transplant recipient.

Deborah Bloch, Mark D Gonzalez, Ann Haight, Carlos Abramowsky, Inci Yildirim

Abstract readCase Reports
In one paragraph

Article in Pediatric transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. RecurrentMedical mycology case reports · 2024
    Article
  3. Polymicrobial Necrotizing Fasciitis in a Dog: The Involvement ofCase reports in veterinary medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Deborah BlochDepartment of Pediatric Infectious Diseases, Emory University, Atlanta, Georgia.ORCID 0000-0002-9386-1074
Mark D GonzalezMicrobiology Laboratory, Children's Healthcare of Atlanta, Atlanta, Georgia.
Ann HaightPediatric Hematology/Oncology and Blood and Marrow Transplant, Aflac Cancer and Blood Disorders Center, Atlanta, Georgia.
Carlos AbramowskyDepartment of Pathology, Emory University, Atlanta, Georgia.
Inci YildirimDepartment of Pediatric Infectious Diseases, Emory University, Atlanta, Georgia.
Emory University · USCenter for Cancer and Blood Disorders · USChildren's Healthcare of Atlanta · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
NCATS NIH HHS TL1 TR002382NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

Necrotizing fasciitis is a life-threatening, rapidly progressing infection of fascia and subcutaneous cellular tissue typically caused by mixed aerobic and anaerobic bacteria. We present a case report of an immunocompromised 4-year-old female with necrotizing fasciitis from a rare fungal organism, Mucor indicus. The patient underwent multiple debridements and was treated for 10 months, first on liposomal amphotericin B (2 months) then posaconazole (8 months). Mucor indicus is a rarely described pathogen with only nine other cases described. Identification of this organism remains a challenge, and the need for further understanding of risk factors and organism susceptibility testing to help guide treatment is crucial.

Indexed as

MucorAmphotericin BBone Marrow TransplantationChild, PreschoolDebridementFasciitis, NecrotizingFemaleHumansImmunocompromised HostMagnetic Resonance ImagingRisk FactorsTreatment OutcomeTriazolesAmphotericin Bliposomal amphotericin BposaconazoleTriazolesbone marrow transplantationMucoralesMucor indicusnecrotizing fasciitis

Identifiers

PMID30246483
PMCPMC6460914
OpenAlexW2894102849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.