Evidence map›Paper›PMID 30246418›Full record

ReviewDiabetic medicine : a journal of the British Diabetic Association2019

Therapies and outcomes of congenital hyperinsulinism-induced hypoglycaemia.

I Banerjee, M Salomon-Estebanez, P Shah, J Nicholson, K E Cosgrove, M J Dunne

Open access · hybridAbstract readReview
In one paragraph

Review in Diabetic medicine : a journal of the British Diabetic Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 133 citations in OpenAlex.

  1. Trial
  2. Review
  3. Congenital Hyperinsulinism With Paternally InheritedJournal of the ASEAN Federation of Endocrine Societies · 2026
    Article
  4. Determinants of hyperinsulinism severity in children with Beckwith-Wiedemann syndrome.The Journal of clinical endocrinology and metabolism · 2026
    Article
  5. Article
  6. Article
  7. [Exercise-induced hyperinsulinism: genetic basis and clinical management].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Diazoxide toxicity in congenital hyperinsulinism: A case report.World journal of clinical pediatrics · 2024
    Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

I BanerjeeDepartment of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
M Salomon-EstebanezDepartment of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.ORCID 0000-0002-8273-6278
P ShahEndocrinology Department, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.
J NicholsonPaediatric Psychosocial Department, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
K E CosgroveFaculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
M J DunneFaculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Manchester Academic Health Science Centre · GBGreat Ormond Street Hospital for Children NHS Foundation Trust · GBManchester University NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital hyperinsulinism is a rare disease, but is the most frequent cause of persistent and severe hypoglycaemia in early childhood. Hypoglycaemia caused by excessive and dysregulated insulin secretion (hyperinsulinism) from disordered pancreatic β cells can often lead to irreversible brain damage with lifelong neurodisability. Although congenital hyperinsulinism has a genetic cause in a significant proportion (40%) of children, often being the result of mutations in the genes encoding the K

Indexed as

Antihypertensive AgentsCongenital HyperinsulinismDiazoxideGastrointestinal AgentsGlucagonHumansHypoglycemiaPancreatectomyPotassium Channels, Inwardly RectifyingPrecision MedicineSulfonylurea ReceptorsTreatment OutcomeAntihypertensive AgentsDiazoxideGastrointestinal AgentsGlucagonPotassium Channels, Inwardly RectifyingSulfonylurea Receptors

Identifiers

PMID30246418
PMCPMC6585719
OpenAlexW2893122299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.