ReviewEvolution; international journal of organic evolution2018
A fly in a tube: Macroevolutionary expectations for integrated phenotypes.
Review in Evolution; international journal of organic evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 167 citations in OpenAlex.
- The evolutionary trajectory of drosophilid walking.Current biology : CB · 2022Pooled it
- A new combined-evidence phylogeny of Toxodontidae (Mammalia, Notoungulata): exploring the radiation and reconstructing hypothetical ancestors.Cladistics : the international journal of the Willi Hennig Society · 2026Article
- Selection, constraints, and contingency drive mosaic patterns of evolution during the carangarian adaptive radiation.Science advances · 2026Article
- Skull morphology of the extinct Tasmanian tiger suggests unique biting style.Nature communications · 2026Article
- Phylogenetic constraints, conservatism, and convergence shape three-dimensional variation in flower morphology of a tropical orchid radiation.The Plant journal : for cell and molecular biology · 2026Article
- Neural crest cell biology shapes lizard skull evolution across evolutionary time scales.Evolution letters · 2026Article
- Functional Evolution and Modular Behaviour in the Carnivoran Mandible.Integrative and comparative biology · 2026Article
- Topological and variational modularity: A case study using the pectoral girdle across the Chrosomus eos-neogaeus hybridization complex.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- The Coevolution of Colour Patterns and Hindwing Shapes on a Large Phylogenetic Scale Reveals Predation-Driven Adaptive Syndromes in Swallowtail Butterflies.Ecology letters · 2026Article
- Article
- Great expectations: altricial developmental strategies are associated with more flexible evolution of limb skeleton proportions in birds.Proceedings. Biological sciences · 2025Article
- Six million years of vole dental evolution shaped by tooth development.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Body mass evolution as a driver of morphological and ecological diversity in terrestrial mammals.BMC ecology and evolution · 2025Article
- Macroevolutionary integration underlies limb modularity in the origin of avian flight.Biology letters · 2025Article
- Assessing the application of landmark-free morphometrics to macroevolutionary analyses.BMC ecology and evolution · 2025Article
- Humerus shape evolved in cetaceans under relaxed selection and random drift.Communications biology · 2025Article
- Emergent network properties link phenotypic modules to ecomorphological divergence in carnivoran mammals.iScience · 2025Article
- A classic key innovation constrains oral jaw functional diversification in fishes.Evolution letters · 2025Article
- Evolutionary integration of forelimb and hindlimb proportions within the bat wing membrane inhibits ecological adaptation.Nature ecology & evolution · 2025Article
- Complexity and weak integration promote the diversity of reef fish oral jaws.Communications biology · 2024Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Phenotypic integration and modularity are ubiquitous features of complex organisms, describing the magnitude and pattern of relationships among biological traits. A key prediction is that these relationships, reflecting genetic, developmental, and functional interactions, shape evolutionary processes by governing evolvability and constraint. Over the last 60 years, a rich literature of research has quantified patterns of integration and modularity across a variety of clades and systems. Only recently has it become possible to contextualize these findings in a phylogenetic framework to understand how trait integration interacts with evolutionary tempo and mode. Here, we review the state of macroevolutionary studies of integration and modularity, synthesizing empirical and theoretical work into a conceptual framework for predicting the effects of integration on evolutionary rate and disparity: a fly in a tube. While magnitude of integration is expected to influence the potential for phenotypic variation to be produced and maintained, thus defining the shape and size of a tube in morphospace, evolutionary rate, or the speed at which a fly moves around the tube, is not necessarily controlled by trait interactions. Finally, we demonstrate this reduced disparity relative to the Brownian expectation for a given rate of evolution with an empirical example: the avian cranium.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.