Evidence map›Paper›PMID 30246166›Full record

ArticleComputational toxicology (Amsterdam, Netherlands)2018

A Workflow for Identifying Metabolically Active Chemicals to Complement

Jeremy A Leonard, Caroline Stevens, Kamel Mansouri, Daniel Chang, Harish Pudukodu, Sherrie Smith, Yu-Mei Tan

Abstract read
In one paragraph

Article in Computational toxicology (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeremy A LeonardOak Ridge Institute for Science and Education, Oak Ridge, TN, USA.
Caroline StevensNational Exposure Research Laboratory, United States Environmental Protection Agency, Athens, GA, USA.
Kamel MansouriOak Ridge Institute for Science and Education, Oak Ridge, TN, USA.
Daniel ChangOffice of Pollution and Prevention of Toxics, United States Environmental Protection Agency, Washington, D.C., USA.
Harish PudukoduNational Exposure Research Laboratory, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Sherrie SmithNational Exposure Research Laboratory, United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Yu-Mei TanNational Exposure Research Laboratory, United States Environmental Protection Agency, Research Triangle Park, NC, USA.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

The new paradigm of toxicity testing approaches involves rapid screening of thousands of chemicals across hundreds of biological targets through use of

Indexed as

ERin vitro screeningmetabolite predictionQSAR

Identifiers

PMID30246166
PMCPMC6145457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.