Evidence map›Paper›PMID 30246017›Full record

ArticleBioMed research international2018

Single Dose Based Ertapenem Prophylaxis Reduces Surgical Site Infection after Selective Hepatectomy of Hepatocellular Carcinoma: A Propensity Score Matching Study.

Bin Tang, Xiaolin Liu, Fei Xing, Chao Wang, Changjun Jia, Songlin Peng, Yang Zhao, Chaoliu Dai, Feng Xu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Bin TangDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.
Xiaolin LiuDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.
Fei XingDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.
Chao WangDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.
Changjun JiaDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.ORCID 0000-0002-6780-6696
Songlin PengDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.
Yang ZhaoDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.
Chaoliu DaiDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.ORCID 0000-0003-4857-9165
Feng XuDepartment of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, China.ORCID 0000-0001-9985-6527
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to assess whether a single dose of ertapenem prophylaxis was more effective than other antibiotics to prevent surgical site infection (SSI) after selective hepatectomy for hepatocellular carcinoma (HCC).

methodsThe data from HCC patients with open hepatectomy between January 2012 and June 2017 in Shengjing Hospital were retrospectively analyzed. These patients were divided into two groups: ertapenem (ER) group, where a single dose of ER was administered; non-ertapenem (NER) group, where NER antibiotics were administered. The SSI rates were compared between two groups before and after matching the propensity scores.

resultsThe enrolled patients consisted of 78 in the ER group and 197 in the NER group. After matching the propensity scores, each group was down-selected to 65 patients. The SSI rate among the matched 130 patients was 14.6%, 7.7% occurred in the ER group and 21.5% in the NER group (

conclusionsA single dose of ER before surgery was more effective in mitigating SSI after selective hepatectomy compared with other antibiotics use. The results imply that the selection of both antibiotics and administration timing is important for the efficacy in preventing SSI.

Indexed as

HepatectomyAgedAnti-Bacterial AgentsAntibiotic ProphylaxisCarcinoma, HepatocellularChinaErtapenemFemaleHumansLiver NeoplasmsMaleMiddle AgedPropensity ScoreRetrospective StudiesSurgical Wound InfectionAnti-Bacterial AgentsErtapenem

Identifiers

PMID30246017
PMCPMC6136539
OpenAlexW2889233498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.