Evidence map›Paper›PMID 30245767›Full record

ArticleThe Neurohospitalist2018

Chronic and Subacute Meningitis: Differentiating Neoplastic From Non-Neoplastic Etiologies.

Mariano Marrodan, Catalina Bensi, Lucas Alessandro, Alejandro D Muggeri, Mauricio F Farez

Open access · greenAbstract read
In one paragraph

Article in The Neurohospitalist, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mariano MarrodanDepartment of Neurology, Epidemiology and Publich Health (CEBES), Institute for Neurological Research Dr. Raúl Carrea (FLENI), Buenos Aires, Argentina.ORCID 0000-0002-4142-8375
Catalina BensiDepartment of Neurology, Epidemiology and Publich Health (CEBES), Institute for Neurological Research Dr. Raúl Carrea (FLENI), Buenos Aires, Argentina.
Lucas AlessandroDepartment of Neurology, Epidemiology and Publich Health (CEBES), Institute for Neurological Research Dr. Raúl Carrea (FLENI), Buenos Aires, Argentina.
Alejandro D MuggeriDepartment of Neuro-Oncology, Epidemiology and Publich Health (CEBES), Neurological Research Dr. Raúl Carrea (FLENI), Buenos Aires, Argentina.
Mauricio F FarezCenter for Research on Neuroimmunological Diseases (CIEN), Epidemiology and Publich Health (CEBES), Neurological Research Dr. Raúl Carrea (FLENI), Buenos Aires, Argentina.
Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAlthough incidence rates vary, infectious, autoimmune, and neoplastic diseases can all cause chronic and subacute meningitis (CSM). We report a Latin-American, single center, CSM case series, analyzing the main clinical characteristics as well as ancillary diagnostic methods differentiating neoplastic from non-neoplastic etiologies.

methodsRetrospective review of CSM cases from a single center in Buenos Aires, Argentina.

resultsSeventy patients with CSM diagnosis were identified, 49 with neoplastic and 21 with non-neoplastic meningitis. A history of previous cancer was significantly higher in neoplastic cases, whereas prevalence of autoimmune disease and fever was more common in non-neoplastic meningitis. C-reactive protein values were higher in non-neoplastic CSM, as was pleocytosis in cerebrospinal fluid analysis. The most frequent etiologies were breast and lung cancer for neoplastic meningitis cases; and idiopathic, tuberculous, and fungal infection for non-neoplastic cases.

conclusionsChronic and subacute meningitis diagnosis is challenging in daily neurological practice. The results we report contribute information from Latin America regarding etiologies of CSM, which can be identified after a comprehensive evaluation in a majority of cases.

Indexed as

chronic meningitisleptomeningitisneoplastic meningitispachymeningitissubacute meningitis

Identifiers

PMID30245767
PMCPMC6146350
OpenAlexW2799727317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.