ArticleDisease markers2018
Gamma-Glutamyltransferase and Risk of Acute Coronary Syndrome in Young Chinese Patients: A Case-Control Study.
Article in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- A Hidden Indicator of Cardiovascular Health: Serum Gamma-Glutamyl Transferase in Focus.Journal of cardiovascular translational research · 2026Review
- Article
- The association between circulating palmitic acid levels and risk of premature coronary artery disease in Chinese patients: a case-control study.BMC cardiovascular disorders · 2025Article
- Correlation of non-esterified fatty acids with acute coronary syndrome risk in young Chinese adults.Frontiers in endocrinology · 2025Article
- Association between serum gamma-glutamyltransferase and early-onset coronary artery disease: a retrospective case-control study.Annals of medicine · 2023Article
- The predictive values of GGT and Hcy in the risk stratifications and prognoses of NSTE-ACS patients.American journal of translational research · 2021Article
- Triglyceride-Glucose Index and Extracellular Volume Fraction in Patients With Heart Failure.Frontiers in cardiovascular medicine · 2021Article
- It's Time to Add Electrocardiography and Echocardiography to CVD Risk Prediction Models: Results from a Prospective Cohort Study.Risk management and healthcare policy · 2021Article
- Serum Gamma Glutamyltransferase Is Associated with 25-Hydroxyvitamin D Status in Elderly Patients with Stable Coronary Artery Disease.International journal of environmental research and public health · 2020Article
- Age-related fatty infiltration of lumbar paraspinal muscles: a normative reference database study in 516 Chinese females.Quantitative imaging in medicine and surgery · 2020Article
- Secreted Frizzled-Related Protein 2 and Extracellular Volume Fraction in Patients with Heart Failure.Oxidative medicine and cellular longevity · 2020Article
- Risk factors for coronary artery disease in young patients with stable angina pectorisTurkish journal of medical sciences · 2019Article
- Association between Gamma-Glutamyl Transferase and Coronary Atherosclerotic Plaque Vulnerability: An Optical Coherence Tomography Study.BioMed research international · 2019Article
- Analysis of the effect of glutamyltransferase on hyperlipidemia based on decision tree.Digital healthArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSerum gamma-glutamyltransferase (GGT) is a biomarker of hepatic disease. Recent studies have shown that GGT may also associate with the risk of coronary artery disease. However, the underlying mechanisms of this association are still unclear.
methodsThis study included 216 young patients with acute coronary syndrome (aged ≤55years) and 227 age-matched controls with normal findings by coronary angiography or coronary computed tomography angiography. We use standard colorimetric techniques and sandwich enzyme-linked immunosorbent assay to measure the levels of GGT and oxidized low-density lipoprotein (ox-LDL), respectively. Traditional risk factors of coronary artery disease, including smoking, diabetes mellitus, hypertension, dyslipidemia, and obesity/overweight, were evaluated according to the current guidelines.
resultsThe levels of GGT were significantly correlated with body mass index and levels of triglyceride, fasting plasma glucose, aspartate aminotransferase, and ox-LDL (all
conclusionsGGT was associated with the risk of ACS in relatively young patients. The link between GGT and the risk of ACS may be dependent on ox-LDL levels, indicating that the prooxidant action is an important pathway for GGT in the development of cardiovascular disease.
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