ReviewTherapeutic advances in neurological disorders2018
Role of polymorphonuclear neutrophils in the reperfused ischemic brain: insights from cell-type-specific immunodepletion and fluorescence microscopy studies.
Review in Therapeutic advances in neurological disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- The Neutrophil to Lymphocyte Ratio in Poststroke Infection: A Systematic Review and Meta-Analysis.Disease markers · 2022Pooled it
- TCRαβTheranostics · 2023Article
- CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells.Neurology(R) neuroimmunology & neuroinflammation · 2022Article
- γδ T Cell in Cerebral Ischemic Stroke: Characteristic, Immunity-Inflammatory Role, and Therapy.Frontiers in neurology · 2022Review
- Macrophage Identification In Situ.Biomedicines · 2021Review
- A cell-penetrating CD40-TRAF2,3 blocking peptide diminishes inflammation and neuronal loss after ischemia/reperfusion.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Interleukin-17 and ischaemic stroke.Immunology · 2021Review
- Tissue Engineering and Its Potential to Reduce Prostate Cancer Treatment Sequelae-Narrative Review.Frontiers in surgery · 2021Review
- Neuroinflammation and microglia/macrophage phenotype modulate the molecular background of post-stroke depression: A literature review.Experimental and therapeutic medicine · 2020Article
- Microglial cell loss after ischemic stroke favors brain neutrophil accumulation.Acta neuropathologica · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polymorphonuclear neutrophil granulocytes (PMNs) are part of the early post-ischemic immune response that orchestrates the removal of infarcted brain tissue. PMNs contribute to secondary brain injury in experimental stroke models. In human patients, high PMN-to-lymphocyte ratios in peripheral blood are predictive of poor stroke outcome. Following earlier studies indicating that the cerebral microvasculature forms an efficient barrier that impedes PMN brain entry even under conditions of ischemia, more recent studies combining intravital two-photon microscopy and
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Registered trials
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