ArticleInternational journal of pediatrics2018
Retrospective Cohort Analysis of Central Line Associated Blood Stream Infection following Introduction of a Central Line Bundle in a Neonatal Intensive Care Unit.
Article in International journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
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Who cites it
8 citing papers in PubMed, 23 citations in OpenAlex.
- From lines to lifelines: a quality improvement study to reduce CLABSI at a level III NICU in LMIC.BMJ open quality · 2026Article
- Towards targeting zero CLABSI in umbilical catheterization: insights from a retrospective study.European journal of pediatrics · 2025Article
- Central Lines and Their Complications in Neonates: A Case Report and Literature Review.Children (Basel, Switzerland) · 2023Review
- Compliance with central venous catheter infection prevention practices after intervention with simulation.Revista brasileira de enfermagem · 2023Article
- The road to zero nosocomial infections in neonates-a narrative review.Acta paediatrica (Oslo, Norway : 1992) · 2021Review
- Reducing late-onset neonatal sepsis in very low birthweight neonates with central lines in a low-and-middle-income country setting.BMJ open quality · 2021Article
- The Effect of Single-Room Care Versus Open-Bay Care on the Incidence of Bacterial Nosocomial Infections in Pre-Term Neonates: A Retrospective Cohort Study.Infectious diseases and therapy · 2021Article
- How to minimize central line-associated bloodstream infections in a neonatal intensive care unit: a quality improvement intervention based on a retrospective analysis and the adoption of an evidence-based bundle.European journal of pediatrics · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCentral Line Associated Bloodstream Infections (CLABSI) constitute a leading cause of morbidity and mortality in neonatal populations. There has been an overwhelming increase in the use of evidence-based care practices, also known as bundles, in the reduction of these infections. In this report, rates of CLABSI and central line utilisation were examined following the introduction of a central line bundle in our Neonatal Intensive Care Unit (NICU) at the Canberra Hospital.
methodsThe research undertaken was a retrospective cohort study in which newborn infants admitted to the Canberra Hospital NICU between January 2011 and December 2016 and had a central line inserted were included in the study. Data regarding central line days, bed days, infection rates, and patient demographics were collected before and after the introduction of an intervention bundle. CLABSI rates were calculated per 1,000 central line days for before (2011-2013) and after (2014-2016) the introduction of the bundle. The postintervention period was retrospectively analysed for compliance, with data regarding the completion of maintenance forms and insertion forms collected.
resultsOverall, the results showed a significant decrease in CLABSI rates from 8.8 per 1,000 central line days to 4.9 per 1,000 central line days in the intervention period (p<0.001). Central line utilisation ratio (CLUR: ratio of central line days to bed days) was also reduced between pre- and postintervention periods, from 0.177 (4414/25013) to 0.13 (3633/27384; p<0.001). Compliance to insertion forms and maintenance forms was observed to increase within the intervention period.
conclusionThe implementation of a central line bundle was effective in reducing both CLABSI rates and dwell time (CLUR) for central venous catheters.
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Registered trials
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