Evidence map›Paper›PMID 30245705›Full record

ArticleJournal of nanomaterials2016

Antibacterial Activity of Partially Oxidized Ag/Au Nanoparticles against the Oral Pathogen

Megan S Holden, Jason Black, Ainsely Lewis, Marie-Claire Boutrin, Elvin Walemba, Theodore S Sabir, Danilo S Boskovic, Aruni Wilson, Hansel M Fletcher, Christopher C Perry

Open access · hybridAbstract read
In one paragraph

Article in Journal of nanomaterials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Local and Systemic Effects ofMicroorganisms · 2023
    Review
  4. Nanoparticles in Dentistry: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Megan S HoldenDivision of Biochemistry, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA.
Jason BlackNorthern Caribbean University, Manchester, Jamaica.
Ainsely LewisNorthern Caribbean University, Manchester, Jamaica.
Marie-Claire BoutrinDivision of Microbiology and Molecular Genetics, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA.
Elvin WalembaDepartment of Earth and Biological Sciences, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA.
Theodore S SabirCollege of Arts and Sciences, Faulkner University, Montgomery, AL 36109, USA.
Danilo S BoskovicDivision of Biochemistry, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA.
Aruni WilsonDivision of Microbiology and Molecular Genetics, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA.
Hansel M FletcherDivision of Microbiology and Molecular Genetics, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA.
Christopher C PerryDivision of Biochemistry, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA.
Loma Linda University · USNorthern Caribbean University · JMFaulkner University · US

Funding

Studies on virulence regulation in PorphyromonasR01DE013664 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2002 to 2011
$3.3M
Mechanisms for adaptation to oxidative stress in Porphyromonas gingivalisR01DE019730 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2009 to 2013
$2.0M
Studies on the virulence regulation in PorphyromonasR01DE025852 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2016 to 2020
$2.0M
ECF sigma factors in adaptation and virulence of Porphyromonas gingivalisR01DE022508 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2012 to 2016
$1.8M
Studies on the virulence regulation in PorphyromonasR56DE013664 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2014 to 2014
$291k
NIDCR NIH HHS R01 DE013664NIDCR NIH HHS R01 DE019730NIDCR NIH HHS R01 DE022508NIDCR NIH HHS R01 DE025852NIDCR NIH HHS R56 DE013664
6 · The paper itself

Abstract

Advances in nanotechnology provide opportunities for the prevention and treatment of periodontal disease. While physicochemical properties of Ag containing nanoparticles (NPs) are known to influence the magnitude of their toxicity, it is thought that nanosilver can be made less toxic to eukaryotes by passivation of the NPs with a benign metal. Moreover, the addition of other noble metals to silver nanoparticles, in the alloy formulation, is known to alter the silver dissolution behavior. Thus, we synthesized glutathione capped Ag/Au alloy bimetallic nanoparticles (NPs)

Identifiers

PMID30245705
PMCPMC6146971
OpenAlexW2288726838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.