Evidence map›Paper›PMID 30245618›Full record

ArticleFrontiers in behavioral neuroscience2018

MouBeAT: A New and Open Toolbox for Guided Analysis of Behavioral Tests in Mice.

Elísabet Bello-Arroyo, Hélio Roque, Alberto Marcos, Javier Orihuel, Alejandro Higuera-Matas, Manuel Desco, Valeria R Caiolfa, Emilio Ambrosio, Enrique Lara-Pezzi, María Victoria Gómez-Gaviro

Abstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elísabet Bello-ArroyoCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Hélio RoqueUnidad de Microscopía e Imagen Dinámica, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Alberto MarcosDepartamento de Psicobiología, Universidad Nacional de Educación a Distancia (UNED), Madrid, Spain.
Javier OrihuelDepartamento de Psicobiología, Universidad Nacional de Educación a Distancia (UNED), Madrid, Spain.
Alejandro Higuera-MatasDepartamento de Psicobiología, Universidad Nacional de Educación a Distancia (UNED), Madrid, Spain.
Manuel DescoDepartamento de Medicina y Cirugía Experimental, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Valeria R CaiolfaUnidad de Microscopía e Imagen Dinámica, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Emilio AmbrosioDepartamento de Psicobiología, Universidad Nacional de Educación a Distancia (UNED), Madrid, Spain.
Enrique Lara-PezziCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
María Victoria Gómez-GaviroDepartamento de Medicina y Cirugía Experimental, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal behavioral tests are essential to understand the bases of neurologic and psychological disorders, which can be evaluated by different methodological and experimental models. However, the quantification of behavioral tests results is limited by the considerable amount of time needed for manual evaluation and the high costs of automated analysis software. To overcome these limitations, we describe here a new, open source toolbox for ImageJ, called Mouse Behavioral Analysis Toolbox (MouBeAT), designed to analyze different behavioral tests in rodents semi-automatically. These tests include Open Field (OF), Elevated Plus Maze (EPM), Y-maze (YM) test and Morris Water Maze (MWM). MouBeAT showed a high correlation with manual evaluation in all the parameters analyzed for all the behavioral tests, reinforcing its value as an accurate analysis tool. This new tool is freely available online.

Indexed as

behavioral testsImageJopen sourcerodentssemi-automated analysis

Identifiers

PMID30245618
PMCPMC6137138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.