Evidence map›Paper›PMID 30245555›Full record

ArticleSocial development (Oxford, England)2018

The BDNF gene val66met polymorphism and behavioral inhibition in early childhood.

Matthew R J Vandermeer, Haroon I Sheikh, Shiva S Singh, Daniel N Klein, Thomas M Olino, Margaret W Dyson, Sara J Bufferd, Elizabeth P Hayden

Abstract read
In one paragraph

Article in Social development (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Matthew R J Vandermeer
Haroon I Sheikh
Shiva S Singh
Daniel N Klein
Thomas M Olino
Margaret W Dyson
Sara J Bufferd
Elizabeth P Hayden
Western University · CACalifornia State University, San Marcos · USStony Brook University · USTemple College · US

Funding

Temperamental Low PE in Preschoolers and Depression RiskR01MH069942 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KLEIN, DANIEL N · 2004 to 2023
$14.2M
NIMH NIH HHS R01 MH069942
6 · The paper itself

Abstract

Stably elevated behavioural inhibition (BI) is an established risk factor for internalizing disorders. This stability may be related to genetic factors, including a valine-to-methionine substitution on codon 66 (

Indexed as

BDNFbehavioural inhibitionchildrenGene-trait interactionlaboratory assessmentval66met

Identifiers

PMID30245555
PMCPMC6142175
OpenAlexW2794369530

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.