High altitude exposure during pregnancy enhances the vulnerability of fetal heart dysfunction to ischemic stress: Epigenetic mechanisms.

Xuesi M Shao

Abstract readEditorialComment

In one paragraph

Article in International journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Newborn brain development comparison of plateau and plain regions: insights from quantitative EEG.Pediatric research · 2026
Article
Impact of Moderate Altitude on Birth Weight and Neonatal Growth Percentiles: A Comparative Analysis of Risk-Free Term Pregnancies from Türkiye.Turkish archives of pediatrics · 2025
Article

4 · The record

Corrections and comments

Comment on
Long-term exposure to high altitude hypoxia during pregnancy increases fetal heart susceptibility to ischemia/reperfusion injury and cardiac dysfunction.2019

5 · Who and what money

Authors and funding

1 author.

Xuesi M ShaoDepartment of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA; Department of Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, USA. Electronic address: mshao@g.ucla.edu.

Funding

Maternal inhaled nicotine leads to aberrant development of hypertensive phenotypeR01HL135623 · NHLBI · LOMA LINDA UNIVERSITY · PI SHAO, XUESI MAX, XIAO, DALIAO · 2017 to 2021

$2.3M

Developing an efficient E-cigarette aerosol generation and exposure system for rodent models with aerosol characteristics equivalent to those inhaled by E-cigarette usersR42DA044788 · NIDA · AUTOMATE SCIENTIFIC, INC. · PI KEWEKORDES, JOSEF, SHAO, XUESI MAX · 2019 to 2020

$884k

Developing an efficient E-cigarette aerosol generation and exposure system for rodent models with aerosol characteristics equivalent to those inhaled by E-cigarette usersR41DA044788 · NIDA · AUTOMATE SCIENTIFIC, INC. · PI KEWEKORDES, JOSEF, SHAO, XUESI MAX · 2018 to 2018

$150k

NHLBI NIH HHS R01 HL135623NIDA NIH HHS R41 DA044788NIDA NIH HHS R42 DA044788

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Altitude SicknessHeart DiseasesReperfusion InjuryAltitudeFemaleFetal HeartHumansHypoxiaPregnancy

Identifiers

PMID30244876

DOI10.1016/j.ijcard.2018.09.053

PMCPMC7263371

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.