Evidence map›Paper›PMID 30244699›Full record

ArticleTranslational research : the journal of laboratory and clinical medicine2018

Metformin as a modulator of myocardial fibrosis postmyocardial infarction via regulation of cardiomyocyte-fibroblast crosstalk.

Giselle C Melendez, Qun Chen, Edward J Lesnefsky

Open access · greenAbstract readComment
In one paragraph

Article in Translational research : the journal of laboratory and clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Giselle C MelendezDepartment of Internal Medicine, Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina; Pathology, Comparative Medicine; Wake Forest School of Medicine, Winston-Salem, North Carolina. Electronic address: gmelende@wakehealth.edu.
Qun ChenDepartment of Internal Medicine, Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Edward J LesnefskyDepartment of Internal Medicine, Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia; Biochemistry, and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia; Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia; The Medical Service of the McGuire Veterans Affairs Medical Center in Richmond, Virginia. Electronic address: edward.lesnefsky@va.gov.
Virginia Commonwealth University · USWake Forest University · US

Funding

Preventing Anthracycline Cardiovascular Toxicity with StatinsR01HL118740 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2013 to 2018
$4.2M
activation of mitochondrial calpain augments cardiac injury in aged heartsR21AG054975 · NIA · VIRGINIA COMMONWEALTH UNIVERSITY · PI CHEN, QUN · 2017 to 2018
$433k
BLRD VA I01 BX001355NHLBI NIH HHS R01 HL118740NIA NIH HHS R21 AG054975
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MetforminMyocytes, CardiacFibroblastsFibrosisHumansInfarctionMyocardial InfarctionMyocardiumMetformin

Identifiers

PMID30244699
PMCPMC9113666
OpenAlexW2807842561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.